江西省首例儿童禽流感H9N2亚型病例的调查分析

发布时间：2018-06-17 15:58

本文选题：流感病毒A型 + HN亚型　；参考：《现代预防医学》2017年05期

【摘要】：目的明确人感染禽流感疫情,查明其感染来源,采取有效措施控制疫情。方法采用现场流调和实验检测相结合的方法对萍乡市1例儿科门急诊发热病例进行筛查、诊断和分析。结果该患儿女性,4岁,于2016年8月2日开始发病,病初表现为流感样症状,反复高热2天,在家口服抗生素等药物治疗无效于2016年8月4日晚上来院就诊,经过抗病毒等有效治疗于2016年8月12日痊愈。患儿咽拭子标本禽流感病毒(H9N2)核酸阳性,病毒分离阳性,基因系列分析显示,分离的H9N2病毒[A/Jiangxi/1/2016/(H9N2)]仍为禽源性特征。患儿发病前后未离开过居住地,未接触过类似病人,但发病近2周有禽类及产品接触史。经医学观察一周,所有密切接触者(包括患儿直系家属共58人)均未出现类似症状。参照卫生部禽流感防控应急预案,采取相应防控措施,疫情没有扩散。结论该病例确诊为江西省首例人感染低致病性禽流感,感染来源可能是禽流感病毒(H9N2)从家禽中获得,无人传人的现象。该例患儿是在我院作为国家流感监测哨点医院日常监测工作中被发现,提示今后应继续加强流感疫情监测工作,加强人感染禽流感的应急贮备、培训和健康宣教。
[Abstract]:Objective to find out the source of human avian influenza infection, and to take effective measures to control it. Methods A case of pediatric outpatient fever in Pingxiang city was screened, diagnosed and analyzed by field flow harmonic test. Results the patient, aged 4 years, began to develop on August 2, 2016. Her initial symptoms showed flu-like symptoms and repeated high fever for 2 days. She was hospitalized on the evening of August 4, 2016 because oral antibiotics and other drugs were ineffective. After antiviral and other effective treatment on August 12, 2016 recovery. Throat swab specimens of children with avian influenza virus H9N2) were positive for nucleic acid and virus isolation. Gene series analysis showed that the isolated H9N2 virus [A / Jiangxir / 1 / 2016 / H9N _ 2] was still avian origin. The children did not leave their place of residence before and after onset, and had no contact with similar patients, but had a history of poultry and product contact in the past 2 weeks. After one week of medical observation, no similar symptoms were found in all close contacts (including 58 immediate family members). Referring to the emergency plan of prevention and control of avian influenza in Ministry of Health, the epidemic did not spread. Conclusion this case is the first case of low pathogenic avian influenza in Jiangxi province. The source of infection may be avian influenza virus H9N2) from poultry. The case was found in our hospital as a national influenza surveillance sentinel hospital daily surveillance work, suggesting that we should continue to strengthen the surveillance of influenza epidemic situation, strengthen the emergency reserve of human infection with avian influenza, training and health education.
【作者单位】：江西省萍乡市人民医院儿科;江西省萍乡市疾控中心;
【分类号】：R725.1;R181.3

【相似文献】