大桑菊饮治疗小儿肺炎支原体支气管炎风热证的临床观察

发布时间：2018-06-23 14:13

本文选题：大桑菊饮 + 肺炎支原体支气管炎　；参考：《广州中医药大学》2013年硕士论文

【摘要】：目的：观察大桑菊饮联合阿奇霉素治疗小儿肺炎支原体支气管炎风热证的临床疗效并进行客观检验,在此基础上,探讨大桑菊饮治疗小儿肺炎支原体支气管炎风热证的作用及中西药联合功效互补的意义,为治疗小儿肺炎支原体支气管炎寻求比较好的治疗方法。方法：本研究设立治疗组和对照组两组,分组采用前瞻性简单随机试验法,将符合纳入标准的60例患者随机分入两组,其中治疗组30例、对照组30例。治疗组采用大桑菊饮联合阿奇霉素方案进行治疗,对照组采用单用阿奇霉素方案治疗,疗程均为21天。治疗前后将对临床观察症状体征评分,并利用统计工具对治疗组与对照组治疗前后的症状体征及MP-IgM指标进行对比分析。成果： 1、症状与体征改善方面,Rdit检验与卡方检验表明,在咳嗽、咯痰症状方面相关的P值0.05,治疗组与对照组比较有显著性差异,表明治疗组在改善咳嗽、咯痰症状方面优于对照组,在退热、肺部体征改善方面相关P值0.05,,无显著性差异,表明治疗组与对照组疗效相当。 2、治疗组和对照组主要症状消失时间比较,经统计学检验,两组在咳嗽与咯痰消失时间方面存在显著性差异(P0.05),表明大桑菊饮加阿奇霉素分散片在咳嗽、咯痰症状消除时间方面优于单独使用阿奇霉素分散片。 3.MP-IgM指标方面,Fish的精确检验的P值明显大于0.05,证明治疗组与对照组在改善MP-IgM值方面无显著性差异。 4、治疗组治疗后痊愈、显效、有效、无效的病例数为4例、20例、5例、1例,总有效率为96.6%,对照组治疗后痊愈、显效、有效、无效的病例数为2例、17例、8例、3例,总有效率为90%,经统计学检验P0.05,两组总有效率不存在显著性差异。结论：大桑菊饮联合阿奇霉素治疗小儿肺炎支原体支气管炎风热证疗效优于单纯阿奇霉素治疗。大桑菊饮治疗小儿肺炎支原体支气管炎风热证疗效显著。
[Abstract]:Objective: to observe the clinical effect of Dasangju decoction combined with azithromycin in treating mycoplasma pneumoniae mycoplasma bronchitis wind and heat syndrome and to carry out objective test. To explore the effect of Dasangju decoction in treating mycoplasma pneumoniae mycoplasma bronchitis wind and heat syndrome and the significance of complementary effect of traditional Chinese and western medicine in the treatment of mycoplasma pneumoniae mycoplasma bronchitis in children. Methods: in this study, the treatment group and the control group were divided into two groups, 30 cases in the treatment group and 30 cases in the control group, and 60 patients who met the inclusion criteria were randomly divided into two groups. The treatment group was treated with Dasangju decoction combined with azithromycin, while the control group was treated with azithromycin alone for 21 days. The clinical symptoms and signs were scored before and after treatment, and the symptoms and signs and MP-IgM indexes of the treatment group and the control group were compared and analyzed by statistical tools before and after treatment. Results: 1. The results of Rdit test and chi-square test showed that there was significant difference between the treatment group and the control group in terms of cough and sputum symptoms (P = 0.05), indicating that the treatment group was improving the cough. The symptoms of expectoration were better than that of the control group (P = 0.05). There was no significant difference between the treatment group and the control group, indicating that the treatment group had the same curative effect as the control group, and the main symptoms disappeared in the treatment group and the control group. By statistical test, there was a significant difference between the two groups in the time of cough and sputum disappearance (P0.05), indicating that Dasangju Yin and Azithromycin dispersible tablets were coughing, The time of eliminating sputum symptoms was better than that of using azithromycin dispersible tablets alone. 3. The precise test of Fish in the index of MP-IgM was significantly greater than 0.05, which proved that there was no significant difference in improving MP-IgM between the treatment group and the control group. The treatment group was cured after treatment. The effective, effective and ineffective cases were 4 cases (20 cases), 20 cases (5 cases) and 1 case (1 case). The total effective rate was 96. 6%. In the control group, the patients were cured, effective and effective. The number of ineffective cases was 2 cases (17 cases), 17 cases (8 cases) and 3 cases (3 cases). The total effective rate was 90. There was no significant difference in the total effective rate between the two groups by statistical test (P0.05). Conclusion: Dasangju decoction combined with azithromycin is superior to azithromycin in the treatment of mycoplasma pneumoniae mycoplasma bronchitis in children. Dasangju decoction is effective in treating mycoplasma pneumoniae mycoplasma in children with wind-heat syndrome.
【学位授予单位】：广州中医药大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R272

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