儿童肺炎危险因素文献研究及临床相关因素的Logistic回归分析

发布时间：2018-06-23 17:34

本文选题：儿童肺炎 + 危险因素　；参考：《辽宁中医药大学》2017年硕士论文

【摘要】：目的:本文通过近20年儿童肺炎文献中危险因素的分析研究,应用儿童肺炎危险因素调查登记表,进行临床资料收集、整理及分析,探寻儿童肺炎的危险及保护因素,为下一步儿童肺炎防治策略提供一定科学依据。方法:利用中国生物医学文献网络版数据库(CBM)以关键词“肺炎”、“儿”、“因素”、“危险”、“高危”在文献中检索获取题录,并利用国内三大权威数据库中国学术期刊全文数据库(CNKI)、维普《中文科技期刊数据库》(CQVIP)、万方中国学术期刊数据库(CSPD),收集1996-2016年国内医学期刊上公开发表的有关儿童肺炎危险因素的文献,运用Note Express软件将重复文献剔除,获得全文2038篇,将符合文献纳入标准的107篇文献进行危险因素出现情况统计分析,将相同的危险因素归类,按出现频次排序。然后基于文献研究的危险因素制定儿童肺炎危险因素调查登记表,自2015年12月-2016年11月,每季度调查100例前来辽宁中医药大学附属医院及大连市儿童医院就诊的儿童,去除信息不全及不符合问卷调查纳入标准者8例,将符合纳入标准的392例问卷调查信息建立数据库,采用Logistic回归分析方法,将单因素分析中有统计学意义(P0.05)的危险因素纳入多因素回归分析中,根据多因素Logistic回归分析结果中B(回归系数)及OR(比数比)确定儿童肺炎的危险因素及保护因素。结果:1.文献研究中入选107篇文献,43篇文献来源于核心期刊,62篇属于统计源期刊,2篇硕士论文,出现频次前5位的危险因素为年龄、环境污染(包括室内与室外)、先心病、季节气候、营养不良。2.多因素Logistic回归分析显示被动吸烟、反复呼吸道感染、大气污染、先天性疾病B0,OR1,为儿童肺炎的危险因素;合理饮食、室内装修5年以上、婴儿期母乳喂养B0,OR1,是儿童肺炎的保护因素。结论:1.文献研究显示年龄(婴幼儿多见)、环境污染(包括室内与室外)、先心病、季节气候、营养不良是儿童常见的危险因素,其他出现频次较低的因素为早产、个人过敏史及免疫功能异常等50项。2.问卷调查研究显示被动吸烟、反复呼吸道感染、大气污染、先天性疾病是儿童肺炎的危险因素;合理饮食、室内装修5年以上、婴儿期母乳喂养是儿童肺炎的保护因素。
[Abstract]:Objective: through the analysis and study of the risk factors in the literature of children's pneumonia in the last 20 years, this paper applies the survey registration form of the risk factors of children's pneumonia, and carries out the clinical data collection, collation and analysis to explore the risk and protective factors of children's pneumonia, and to provide a scientific basis for the next strategy of prevention and control of pneumonia in children. The document network version database (CBM) uses key words "pneumonia", "son", "factor", "risk", "high-risk" to retrieve the title in the literature, and uses the three major authoritative database of China's Chinese academic journal full text database (CNKI), VP < Chinese Sci-tech Journal Database > (CQVIP), Wan Fang Chinese academic journal database (CSPD), and collect 1 The literature on the risk factors of children pneumonia published in the domestic medical journal in 996-2016 years, using Note Express software to remove the repeated documents and obtain the full text of 2038 articles, which will conform to the standard 107 documents to analyze the occurrence of risk factors, classify the same risk factors and sort out the occurrence frequency. Based on the risk factors of literature study, the registration form of the risk factors for children's pneumonia was made. From November -2016 December 2015, 100 children who came to the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine and Dalian children's hospital were investigated each quarter, and 8 cases were removed from the information of incomplete information and those who did not conform to the questionnaire, which would be in line with the standard of 392. The database was set up by the questionnaire survey information. The Logistic regression analysis was used to integrate the risk factors of statistical significance (P0.05) in the single factor analysis into multiple factor regression analysis. The risk factors and protective factors of children pneumonia were determined according to the B (regression coefficient) and OR (ratio Ratio) in the results of multi factor Logistic regression analysis. The results were 1. articles. In the study, 107 articles were selected, 43 were from the core periodicals, 62 were statistical source journals and 2 master's papers. The risk factors for the first 5 were age, environmental pollution (including indoor and outdoor), congenital heart disease, seasonal climate, and malnutrition.2. multiple factors Logistic regression analysis showed passive smoking, recurrent respiratory infection, Gas pollution, congenital disease B0, OR1, is a risk factor for children pneumonia; reasonable diet, indoor decoration for more than 5 years, infant breastfeeding B0, OR1, is a protective factor for children pneumonia. Conclusion: 1. literature studies show that age (many children), environmental pollution (including indoor and outdoor), congenital heart disease, seasonal climate, malnutrition are common children The risk factors and other low frequency factors were preterm labor, individual allergy history and immune function abnormality in 50.2. questionnaires, which showed that passive smoking, recurrent respiratory infection, air pollution, and congenital disease were risk factors for children pneumonia; reasonable diet, indoor decoration for more than 5 years and infant breastfeeding were the protection of pneumonia in children. Protect the factors.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R725.6

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