儿童烧伤脓毒症的高危因素分析

发布时间：2018-06-27 04:24

本文选题：小儿烧伤 + 脓毒症　；参考：《宁夏医科大学》2017年硕士论文

【摘要】：目的探讨儿童烧伤脓毒症发生的相关危险因素,为预防儿童烧伤脓毒症提供理论依据及临床指导。方法通过回顾性分析2010年1月1日-2015年12月31日间在宁夏医科大学总医院住院治疗的0-12岁烧伤合并脓毒症120例及无脓毒症2030例患儿病历资料,分为病例组及对照组,观察性别、年龄、烧伤面积、烧伤深度、烧伤程度、烧伤后是否及时复苏、烧伤后是否及时清创、烧伤后入院时间、是否合并吸入性损伤、是否合并其他部位感染、是否合并休克及烧伤类型等相关变量及其与患儿发生脓毒症的相关性,将有统计学意义的指标纳入非条件Logistic回归分析,筛查出与儿童烧伤并发脓毒症相关的危险因素。结果本研究收集病例总数为2150例,其中脓毒症患儿有120例,发生率5.58%。多因素分析显示:合并吸入性损伤(OR=5.793),有延迟复苏(OR=4.703)、合并休克(OR=3.904)、合并其余部位感染(OR=3.386)、重度烧伤(OR=3.028)、烧伤面积25%(OR=1.658)、年龄越小(OR=1.402)、未及时入院(OR=1.004)是烧伤患儿并发脓毒症的危险因素,而浅度烧伤(OR=0.760)和及时清创(OR=0.031)是保护因素。结论1.儿童烧伤后发生脓毒症是多个因素共同作用的结果,各因素之间可以相互影响,互相作用。2.临床上应加强对儿童烧伤脓毒症高危因素的重视,并采取有效措施降低脓毒症的患病率。
[Abstract]:Objective to explore the risk factors of burn sepsis in children and to provide theoretical basis and clinical guidance for the prevention of burn sepsis in children. Methods the medical records of 120 burn patients with sepsis aged 0-12 and 2030 children without sepsis who were hospitalized in General Hospital of Ningxia Medical University from January 1, 2010 to December 31, 2015 were retrospectively analyzed. The patients were divided into two groups: case group and control group. Age, area, depth, degree of burn, resuscitation after burn, debridement after burn, admission time after burn, inhalation injury, infection in other parts, In order to screen out the risk factors associated with sepsis in children with burn and other related variables such as shock and burn type and their correlation with sepsis the statistically significant indexes were included in the non-conditional logistic regression analysis in order to screen out the risk factors associated with sepsis in children. Results 2150 cases were collected in this study, of which 120 cases were sepsis, the incidence was 5.58%. Multivariate analysis showed that complicated inhalation injury (OR5.793), delayed resuscitation (OR4.703), shock (OR3.904), infection of other sites (OR3.386), severe burn (OR3.028), burn area of 25% (OR1.658), younger age (OR1.402), delayed hospitalization (OR1.004) were the risk factors of sepsis in burn children. Shallow burn (ORO 0.760) and timely debridement (ORO 0.031) were protective factors. Conclusion 1. Sepsis after burns in children is the result of multiple factors, which can interact with each other. 2. 2. In clinic, we should pay more attention to the high risk factors of burn sepsis in children, and take effective measures to reduce the prevalence rate of sepsis.
【学位授予单位】：宁夏医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R726.5

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