肾上腺皮质激素治疗儿科重症感染的临床观察

发布时间：2018-06-28 08:44

本文选题：肾上腺皮质激素 + 儿科　；参考：《临床医药文献电子杂志》2016年53期

【摘要】：目的探讨分析临床上对重症感染患儿应用肾上腺皮质激素进行治疗的具体临床疗效,为进一步合理有效的治疗提供科学依据。方法随机选取2014年8月~2016年8月在我院接受治疗的86例儿科重症感染患儿作为研究对象,采用随机数字表的方法将研究对象分为实验组(43例)和对照组(43例),对照组研究对象应用抗生素常规抗感染药物和补钙、补钾药物及保护心肌、胃粘膜药进行治疗,实验组研究对象在对照组治疗方法的基础上再应用肾上腺皮质激素进行治疗,观察分析实验组和对照组研究对象具体的临床疗效。结果不同方法治疗后,实验组和对照组研究对象在ESR、皮质醇、CRP和中性粒细胞等指标方面,实验组均明显低于对照组,两组比较差异显著,差别具有统计学意义(P0.05);不同方法治疗后,实验组研究对象在恢复正常体温和完全康复所需时间等方面均明显少于对照组研究对象,两组比较差异显著,差别具有统计学意义(P0.05);不同方法治疗后,实验组和对照组研究对象并发症的发生率分比为51.16%和81.39%,两组比较差异显著,差别具有统计学意义(P0.05)。结论临床上应用肾上腺皮质激素对重症感染患儿进行治疗的临床疗效显著,安全性高,并发症的发生率低,患儿恢复健康时间短,生活质量明显提高,值得进一步的应用和推广。
[Abstract]:Objective to investigate the clinical effect of adrenocortical hormone in the treatment of children with severe infection in order to provide scientific basis for further rational and effective treatment. Methods 86 pediatric children with severe infection were randomly selected from August 2014 to August 2016. The subjects of the study were divided into experimental group (43 cases) and control group (43 cases) by random digital table. The subjects of control group were treated with antibiotics, routine anti-infective drugs and calcium, potassium supplements and drugs to protect myocardium and gastric mucosa. The subjects of the experimental group were treated with adrenocortical hormone on the basis of the treatment methods of the control group, and the specific clinical effects of the experimental group and the control group were observed and analyzed. Results the ESRs, cortisol CRP and neutrophils in the experimental group and the control group were significantly lower than those in the control group after different treatment, and the difference between the two groups was significant. The difference was statistically significant (P0.05); after different methods of treatment, the experimental group in the recovery of normal body temperature and complete recovery time were significantly lower than the control group, the two groups were significantly different. The difference was statistically significant (P0.05); after different treatment, the incidence of complications in the experimental group and control group was 51.16% and 81.39, the difference between the two groups was significant (P0.05). Conclusion the clinical effect of adrenocortical hormone on children with severe infection is significant, the safety is high, the incidence of complications is low, the recovery time is short, and the quality of life is obviously improved. It is worthy of further application and popularization.
【作者单位】：湖北省黄石市妇幼保健院儿科;
【分类号】：R725.1

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