辨证使用中成药治疗小儿急性上呼吸道感染的疗效评价研究

发布时间：2018-07-03 15:46

本文选题：小儿感冒 + 文献研究　；参考：《南京中医药大学》2012年硕士论文

【摘要】：本论文主要分理论研究与临床研究两部分。理论研究通过对中医古代及现代医学文献的系统研究,探讨儿童感冒(急性上呼吸道感染)的发生、发展、变化规律,总结治疗小儿感冒的有效方药,为更好地指导临床,合理运用中医中药治疗本病提供科学的依据。临床研究目的：观察感冒治疗前后的症状及体征积分变化,评价方案中试验药物治疗小儿感冒的有效性和安全性。初步探讨病原学与证型间的相关性。方法：按照随机、平行对照的临床试验方法,将170例符合诊断标准的感冒患儿,分为中药组85例和西药组85例,并对其辨证分型,分别服中成药及抗病毒西药。结果：①临床疗效：试验组临床痊愈占39.02%,显效占45.12%,愈显率为84.14%；对照组临床痊愈率为25.61%,显效率为42.68%,愈显率为68.28%。两组愈显率比较,试验组优于对照组(84.14%68.28%)；②症状改善方面,治疗后症候积分及在流涕、纳呆、大便等症状改善方面(P0.05),说明中药组疗效优于西药组；③体温恢复正常时间方面,差异无统计学意(P0.05),提示中药组、西药组在体温恢复正常时间疗效相当；④病毒检测率较高(57.76%)。结论：中成药治疗小儿感冒疗效确切,能改善众多临床症状；无明显不良反应；患儿依从性高,适合推广普及,应用前景良好。
[Abstract]:This thesis is divided into two parts: theoretical research and clinical research. Through the systematic study of the ancient and modern medical literature of TCM, the occurrence, development and change of children's colds (acute upper respiratory tract infection) were discussed, and the effective prescriptions for the treatment of children's colds were summarized. In order to better guide clinical, rational use of traditional Chinese medicine to provide scientific basis for the treatment of this disease. Objective: to observe the changes of symptom and sign scores before and after treatment of colds and to evaluate the efficacy and safety of experimental drugs in the treatment of infantile colds. To explore the correlation between etiology and syndromes. Methods: according to the clinical trial method of random and parallel control, 170 children with colds who met the diagnostic criteria were divided into Chinese medicine group (85 cases) and western medicine group (85 cases). Results: the clinical curative effect of the trial group was 39.02%, the remarkable effect was 45.12%, the recovery rate was 84.14, the clinical cure rate of the control group was 25.61%, the effective rate was 42.68, and the effective rate was 68.28%. Compared with the two groups, the experimental group was superior to the control group (84.14h.28%) in improving the symptoms, the symptom score after treatment and the improvement of symptoms such as runny, anodyne and stool (P0.05), which indicated that the curative effect of the traditional Chinese medicine group was better than that of the western medicine group (84.14h.28%), and the recovery time of body temperature in the Chinese medicine group was better than that in the western medicine group. The difference was not statistically significant (P0.05), suggesting that the traditional Chinese medicine group, Western medicine group in the body temperature recovery time equivalent to the detection rate of virus 4 (57.76%). Conclusion: Chinese patent medicine is effective in treating infantile colds, it can improve many clinical symptoms, there is no obvious adverse reaction, the compliance of children is high, it is suitable for popularizing, and the application prospect is good.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R272

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