不同碘营养水平儿童甲状腺结节患病情况及结节类型的研究
发布时间：2018-07-29 17:54
【摘要】：目的了解不同碘营养水平儿童甲状腺结节患病情况,探讨碘过量对儿童甲状腺结节类型的影响。方法选择供碘盐地区的3个县调查,每个县随机抽取8-10岁学生(男、女各半)200人;在水源性高碘地区抽取水碘含量100-1 100μg/L的13村为调查点,每个调查点随机抽取学校8-10岁学生(男、女各半)100名。对抽取的学生随机采集1次性尿样检测尿碘,用B超法检测甲状腺结节情况,对学校所在的村随机采集2份末梢水样检测水碘。结果检查2 092名8-10岁儿童的甲状腺,检出甲状腺结节患者138例,甲状腺结节总检出率为6.6%。其中,实质性结节占82.6%(114/138),囊实性占16.7%(23/138),囊性占0.7%(1/138)。尿碘中位数100-299μg/L、300-699μg/L、700-1 163μg/L的儿童甲状腺结节检出率经统计有显著差异(χ~2=22.17,P0.01);甲状腺实质性结节所占比例无差异(χ~2=2.82,P0.05)。结论碘营养过量可能会造成儿童甲状腺结节患病增加,但对甲状腺结节的囊、实性患病可能无影响。
[Abstract]:Objective to investigate the prevalence of thyroid nodules in children with different iodine nutrition levels and to explore the effect of iodine excess on thyroid nodules in children. Methods A total of 200 students (male and half female) aged 8 to 10 years old were randomly selected from 3 counties in iodized salt area, and 13 villages with 100 ~ 1 100 渭 g / L iodine content in water source high iodine area were selected as investigation points. A random sample of 100 school students aged 8-10 years (male and half female) was randomly selected from each survey site. Urine iodine was detected by random sampling of urine samples from students, thyroid nodule was detected by B-ultrasound, and iodine was detected by 2 samples of peripheral water in the village where the school was located. Results the thyroid gland of 2 092 children aged 8 to 10 years was examined, 138 cases of thyroid nodules were detected, the total detection rate of thyroid nodules was 6. 6%. Of these, 82.6% (114 / 138) were parenchymal nodules, 16.7% (23 / 138) were cystic, and 0.7% (1 / 138) were cystic. There was significant difference in the detection rate of thyroid nodules between 300-699 渭 g / L and 700-1 163 渭 g / L in children with urinary iodine median of 100-299 渭 g / L (蠂 ~ 2 = 22.17 / P 0.01), but there was no significant difference in the proportion of thyroid parenchymal nodules (蠂 ~ (2) 2.82 ~ (2) P ~ (0.05). Conclusion excessive iodine nutrition may increase the incidence of thyroid nodules in children, but there may be no effect on the solid disease of thyroid nodules.
【作者单位】： 沧州市疾病预防控制中心;河北省疾病预防控制中心地方病防治所;
【分类号】：R725.8
本文编号：2153528
[Abstract]:Objective to investigate the prevalence of thyroid nodules in children with different iodine nutrition levels and to explore the effect of iodine excess on thyroid nodules in children. Methods A total of 200 students (male and half female) aged 8 to 10 years old were randomly selected from 3 counties in iodized salt area, and 13 villages with 100 ~ 1 100 渭 g / L iodine content in water source high iodine area were selected as investigation points. A random sample of 100 school students aged 8-10 years (male and half female) was randomly selected from each survey site. Urine iodine was detected by random sampling of urine samples from students, thyroid nodule was detected by B-ultrasound, and iodine was detected by 2 samples of peripheral water in the village where the school was located. Results the thyroid gland of 2 092 children aged 8 to 10 years was examined, 138 cases of thyroid nodules were detected, the total detection rate of thyroid nodules was 6. 6%. Of these, 82.6% (114 / 138) were parenchymal nodules, 16.7% (23 / 138) were cystic, and 0.7% (1 / 138) were cystic. There was significant difference in the detection rate of thyroid nodules between 300-699 渭 g / L and 700-1 163 渭 g / L in children with urinary iodine median of 100-299 渭 g / L (蠂 ~ 2 = 22.17 / P 0.01), but there was no significant difference in the proportion of thyroid parenchymal nodules (蠂 ~ (2) 2.82 ~ (2) P ~ (0.05). Conclusion excessive iodine nutrition may increase the incidence of thyroid nodules in children, but there may be no effect on the solid disease of thyroid nodules.
【作者单位】： 沧州市疾病预防控制中心;河北省疾病预防控制中心地方病防治所;
【分类号】：R725.8
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