小柴胡汤合葛根汤对肺部感染高热患儿血清学指标的影响分析

发布时间：2018-08-05 16:00

【摘要】：目的分析小柴胡汤合葛根汤对小儿肺部感染高热患者血清学指标的影响。方法选取2016年2月-2017年2月于医院就诊的肺部感染致高热患儿共80例,随机分为治疗组和对照组,每组各40例;两组患儿均采用常规疗法,治疗组在此基础上给予口服小柴胡汤合葛根汤,对比两组患儿的治疗效果和血清指标。结果治疗后,治疗组的总有效率90.0%高于对照组的57.5%;治疗组的中医症状积分和临床肺部感染评分(CPIS)较对照组更低;治疗组患儿的血清白介素-6(IL-6)水平和肿瘤坏死因子-α(TNF-α)水平较对照组更低;治疗组的退热时间、咳嗽缓解时间和住院时间低于对照组;两组比较差异均有统计学意义(P0.05)。结论小柴胡汤合葛根汤在临床治疗小儿肺部感染导致的高热患儿时,有效降低了其血清IL-6和TNF-α炎性细胞因子的水平,取得了很好的治疗效果。
[Abstract]:Objective to analyze the effect of Xiao Chaihu Tang and Gegen Decoction on the serological indexes of children with high fever in lung infection. Methods 80 children with high fever caused by lung infection in the hospital in February -2017 in February 2016 were selected and randomly divided into treatment group and control group, each group was 40 cases. The two groups were treated with conventional therapy, and the treatment group was given the mouth on the basis of this. After the treatment, the total effective rate of the treatment group was 90% higher than that of the control group, and the TCM symptom score and the clinical pulmonary infection score (CPIS) were lower than those of the control group. The serum interleukins -6 (IL-6) level and tumor necrosis factor - alpha in the treatment group were compared with that of the control group after treatment. The level of (TNF- alpha) was lower than that of the control group; the time of fever, the time of cough remission and the time of hospitalization were lower in the treatment group than in the control group, and the difference between the two groups was statistically significant (P0.05). Conclusion the serum IL-6 and TNF- alpha inflammatory cytokines were effectively reduced by the small Chaihu Decoction and Gegen Decoction in the high fever caused by children's pulmonary infection. The level of the treatment has achieved good therapeutic effect.
【作者单位】：海南医学院中医学院中医妇儿科教研室;深圳市中医院儿科;海口市中医医院儿科;海南医学院中医学院中西结合妇儿教研室;
【基金】：国家自然科学基金委员会资助项目(81503616) 中国博士后科学基金资助项目(2016M590840) 广东省科技计划基金资助项目(2014A020221003)
【分类号】：R725.6

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