中药内服联合穴位敷贴治疗小儿哮喘缓解期的临床观察

发布时间：2018-08-05 18:36

【摘要】：研究目的：哮喘是儿童时期最常见的肺系疾病之一,本研究旨在评价中药内服联合穴位贴敷的治疗小儿哮喘缓解期的临床疗效,主要观察在治疗前后的主症积分和次症积分等指标。研究方法：选取90例符合支气管哮喘的诊断标准的缓解期的患儿,随机分为治疗组和对照组,两组均45例,在年龄、性别及病情方面两组患儿在入组前差异无统计学意义(P0.05),具有可比性。治疗组用中药内服联合穴位敷贴治疗,对照组采用布地奈德雾化吸入治疗；两组均进行3个月的治疗和随访；治疗和随访结束后,比较两组患儿主症积分、次症积分和中医证候总积分的改善的情况,以此比较两种不同的治疗方案来治疗小儿哮喘缓解期的临床效果。研究结果：研究过程中,共完成研究81例,治疗组40例,对照组41例,有脱落病例9例,其中治疗组5例,对照组4例,我们将脱落病例剔除,统计结果汇报如下： 1.在主症改善方面,在改善呼吸道的感染次数、哮喘的发作时间、哮喘的发作次数方面,治疗组优于对照组(P0.05)；在改善哮喘发作程度方面,治疗组无明显优势(P0.05)。 2.在次症积分改善方面,治疗组较对照组有明显优势(P0.05)。 3.中医证候疗效评价,治疗组临床痊愈7例,显效28例,有效5例,无效0例,临床痊愈显效率为87.5%,总有效率100%,对照组临床痊愈2例,显效10例,有效27例,无效2例,临床痊愈显效率29.26%,总有效率95.12%,治疗组较对照组有明显优势(P0.05)。 4.治疗组在治疗和随访过程中,未见明显不良反应。结论：健脾补肾中药内服联合穴位敷贴的治疗小儿哮喘缓解期具有肯定的疗效,它在改善患儿的远期临床表现方而有明显的优势,可安全使用。
[Abstract]:Objective: asthma is one of the most common pulmonary diseases in childhood. Main symptom score and secondary symptom score were observed before and after treatment. Methods: ninety children with remission period who met the diagnostic criteria of bronchial asthma were randomly divided into treatment group and control group. There was no significant difference between the two groups before entering the group (P0.05), which was comparable. The treatment group was treated with traditional Chinese medicine combined with acupoint application, the control group was treated with budesonide atomization inhalation; the two groups were treated for 3 months and followed up; after treatment and follow-up, the main symptom scores of the two groups were compared. In order to compare the clinical effect of two different treatment schemes in treating children with asthma in remission stage, the improvement of sub-symptom integral and total integral of TCM syndromes were compared. Results: in the course of the study, 81 cases were completed, 40 cases in the treatment group, 41 cases in the control group, 9 cases in the control group, 5 cases in the treatment group and 4 cases in the control group. The results are reported as follows: 1. In the main symptoms improvement, in improving respiratory tract infection, asthma attack time, asthma attack times, the treatment group is better than the control group (P0.05), in improving the asthma attack, the treatment group has no significant advantage (P0.05). In terms of the improvement of symptom scores, the treatment group has significant advantages over the control group (P0.05). In the treatment group, 7 cases were cured, 28 cases were effective, 5 cases were effective, 0 cases were ineffective, the effective rate was 87.5%, and the total effective rate was 100%. In the control group, 2 cases were cured, 10 cases were markedly effective, 27 cases were effective, and 2 cases were ineffective. The effective rate of clinical recovery was 29.26 and the total effective rate was 95.12. The treatment group had obvious advantages compared with the control group (P0.05). In the treatment group, no significant adverse reactions were observed during the course of treatment and follow-up. Conclusion: Chinese herbal medicine for invigorating spleen and tonifying kidney combined with acupoint application has definite curative effect on children with asthma in remission period. It has obvious advantages in improving the long-term clinical manifestation of children and can be safely used.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R272

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