营养风险筛查对重症肺炎儿童不良临床结局的评估

发布时间：2018-08-25 20:40

【摘要】：目的采用儿科营养不良评估筛查工具(STAMP)调查重症肺炎儿童营养风险发生情况,分析营养风险与不良临床结局的关系。方法选择216例重症肺炎患儿为研究对象,根据STAMP评分分为高度营养风险组(HR组,n=98)、中度营养风险组(MR组,n=65)和低度营养风险组(LR组,n=53)。空腹抽血检测胰岛素样生长因子-1(IGF-1)、脂联素、瘦素、非酯化脂肪酸(NEFA)、白蛋白、转铁蛋白、前白蛋白、视黄醇结合蛋白(RBP)水平,记录不良临床结局。结果 HR组的血清IGF-1、瘦素、脂联素、前白蛋白、RBP水平低于LR组和MR组(P0.05),而血清NEFA水平高于LR组和MR组(P0.05)。HR组中入住ICU患儿的比例高于LR组和MR组(P0.05);HR组机械通气时间长于LR组和MR组(P0.05);HR组住院时间长于LR组和MR组(P0.05),并发症发生率高于LR和MR组(P0.05)。结论营养风险筛查对评估重症肺炎儿童临床结局有重要价值,高度营养风险患儿有更多的不良临床结局,应尽早给予合理的营养支持。
[Abstract]:Objective to investigate the incidence of nutritional risk in children with severe pneumonia by (STAMP), and to analyze the relationship between nutritional risk and poor clinical outcome. Methods 216 children with severe pneumonia were divided into high nutritional risk group (HR group), moderate nutritional risk group (MR group) and low nutritional risk group (LR group) according to STAMP score. The levels of insulin like growth factor-1 (IGF-1), adiponectin, leptin, nonesterified fatty acid (NEFA), albumin, transferrin, prealbumin, retinol binding protein (RBP) were measured in fasting blood samples. Results Serum IGF-1, leptin and adiponectin in HR group, The serum NEFA level was higher than that in LR group and MR group (P0.05). The percentage of children admitted to ICU in HR group was higher than that in LR group and MR group (P0.05). The duration of mechanical ventilation in HR group was longer than that in LR group and MR group (P0.05). The incidence of complications in MR group and LR group (P0.05) was higher than that in LR and MR group (P0.05). Conclusion nutritional risk screening is of great value in evaluating the clinical outcome of children with severe pneumonia. Children with high nutritional risk have more adverse clinical outcomes and should be given reasonable nutritional support as soon as possible.
【作者单位】：山东省滨州市人民医院儿科;山东省滨州市人民医院肿瘤科;
【分类号】：R725.6;R723

【相似文献】