新疆维、汉、哈三民族儿童脂肪重聚年龄的比较

发布时间：2018-10-20 10:05

【摘要】：目的:通过对新疆维吾尔族(维族)、汉族、哈萨克族(哈族)儿童生长发育指标随访调查,获得儿童脂肪重聚(Adiposity Rebound,AR)年龄,比较维、汉、哈三民族儿童AR分布差异性,从而探讨AR年龄对儿童肥胖的预测价值,为制定儿童肥胖干预策略提供科学依据。方法:依托国家自然科学基金(81260440),前期于2014年完成乌鲁木齐市、克拉玛依市、阿勒泰市、伊宁市四地区3~9岁儿童体格发育调查,进行父母填写问卷调查获得儿童家庭状况、出生情况、父母生长指标等信息。本研究对小于7岁的儿童在每年4月及10月进行两次身高、体重、腰围测量的随访,共随访5次,观察BMI、BSA、WHtr等指标变化情况;应用SAS 9.3软件对随访BMI进行广义相加模型拟合,得出个体AR年龄,应用SPSS 21.0软件描述维、汉、哈三民族儿童AR年龄分布情况并进行比较;分析肥胖儿童和非肥胖儿童中,维、汉、哈三民族AR年龄的分布特征并进行比较;分析AR年龄与生长发育指标的相关性;比较三民族AR年龄与随访期间BMI等级变化的关系;采用多重线性回归探究维、汉、哈三民族AR年龄的影响因素。结果:共随访2453名儿童,其中维族875人,汉族1050人,哈族528人;男童1276人,女童1177人。儿童个体AR年龄多发生于4~6岁,维、汉、哈三民族AR年龄分布差异有统计学意义(F=172.309,P0.001);非肥胖与肥胖组,三民族AR年龄差异仍具有统计学意义(F=162.092,P0.001;F=20.87,P0.001);随访儿童AR年龄与BMI、BSA、WHtr具有一定相关性;随访期间,BMI分级由正常变为肥胖组与肥胖变为正常组相比,两组AR年龄差异有统计学意义(t=-10.123,P0.001),且前者AR年龄小于后者;多重线性回归结果显示,家庭收入是维、汉、哈三民族儿童AR年龄的共同影响因素,其他影响因素不完全一致。结论:维、汉、哈三民族AR年龄分布明显不同,AR年龄可作为儿童肥胖的一个预测指标。
[Abstract]:Objective: to investigate the growth and development indexes of Uygur, Han and Kazakh children in Xinjiang Uygur, and to obtain the age of Adiposity Rebound,AR and the difference of AR distribution among children of Uygur, Han and Kazakh nationalities. To explore the predictive value of AR age on childhood obesity and to provide scientific basis for the formulation of intervention strategies for childhood obesity. Methods: based on the National Natural Science Foundation (81260440), the physical development survey of 3-year-old children in Urumqi, Karamay, Altay and Yining was completed in 2014. Birth status, parental growth indicators and other information. In this study, children younger than 7 years of age were followed up twice a year in April and October to measure height, weight and waist circumference for 5 times, to observe the changes of BMI,BSA,WHtr and other indexes, and to use SAS 9.3 software to carry out generalized additive model fitting to follow up BMI. The age distribution of AR in children of Uygur, Han and Kazakh nationalities was described by using SPSS 21.0 software, and the distribution characteristics of AR age in obese children and non-obese children were analyzed and compared. To analyze the correlation between the age of AR and the growth and development index, to compare the relationship between the age of AR and the change of BMI grade during the follow-up period, and to explore the influence factors of AR age of the three nationalities by multiple linear regression. Results: a total of 2453 children were followed up, including 875 Uygur, 1050 Han, 528 Kazakh, 1276 boys and 1177 girls. The age distribution of AR in children aged 4 to 6 years was statistically significant (F172.309, P0.001), and the age distribution of AR in non-obese and obese groups was significantly higher than that in non-obese and obese groups, but there was a significant difference in the age distribution of AR between Uygur, Han and Kazakh nationalities (P 0.001). The age difference of AR in the three nationalities was still statistically significant (FF162.092P0.001F0.87 P0.001), the age of AR was correlated with BMI,BSA,WHtr in children followed up, during the follow-up period, the BMI grade changed from normal to obese and obese to normal. The age difference of AR between the two groups was statistically significant (t = 10.123, P0.001), and the AR age of the former was lower than that of the latter, and the multiple linear regression showed that family income was the common influencing factor of AR age of children of Uygur, Han and Kazakh nationalities, while the other influencing factors were not completely consistent. Conclusion: the age distribution of AR in Uygur, Han and Kazakh nationalities is obviously different. AR age can be used as a predictor of childhood obesity.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R723.14

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