健脾益肾法治疗特发性矮小患儿的临床观察

发布时间：2018-11-14 09:34

【摘要】：目的：观察健脾益肾法治疗特发性矮小患儿的临床疗效,探讨其作用机制,评价中医药治疗本病的临床价值,丰富中医治疗学内容。 方法：60例(2010年9月～2011年12月)病例均来自江苏省中医院儿科门诊,分治疗组与空白对照组,各30例,进行治疗前后的疗效对比。 结果：健脾益肾方药治疗特发性身材矮小患儿的总有效率为68.13%。治疗后患儿身高、生长速度与治疗前相比,有显著差异,食欲不振、毛发稀疏、形体消瘦、大便不调、畏寒怕冷等中医症候与治疗前相比,也有极显著差异,在治疗3个月即体现其优势。但6个月后骨龄增长无明显差异。治疗前后未出现明显不良反应。健脾益肾方的治疗费用较低,为大多数患儿家长所接受,具有较好的临床意义。 结论：特发性身材矮小患儿存在脾肾不足的病理机制,健脾益肾法是治疗特发性身材矮小患儿的有效治则,中医药治疗本病有一定的临床意义。
[Abstract]:Objective: to observe the clinical effect of invigorating spleen and tonifying kidney in treating children with idiopathic dwarfism, to explore its mechanism, to evaluate the clinical value of traditional Chinese medicine (TCM) in treating this disease, and to enrich the contents of TCM therapy. Methods: 60 cases (from September 2010 to December 2011) were divided into treatment group and blank control group (n = 30). The therapeutic effects were compared before and after treatment. Results: the total effective rate of invigorating spleen and tonifying kidney was 68.13 in children with idiopathic short stature. After treatment, there were significant differences in height and growth rate between the children after treatment and before treatment. There were also significant differences between before treatment and before treatment, such as loss of appetite, sparse hair, thin body, unadjusted defecation, fear of cold, and so on. Its advantage is demonstrated in 3 months of treatment. But there was no significant difference in bone age after 6 months. There was no obvious adverse reaction before and after treatment. The treatment cost of Jianpi Yishen prescription is lower, which is accepted by most parents of children, and has good clinical significance. Conclusion: there is pathological mechanism of deficiency of spleen and kidney in children with idiopathic short stature. Strengthening spleen and tonifying kidney is an effective treatment principle for children with idiopathic short stature. Chinese medicine has certain clinical significance in treating this disease.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R272

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