妊娠合并甲状腺功能亢进症对围生儿的影响
发布时间：2018-11-18 19:09
【摘要】：目的：探讨妊娠期间甲状腺功能亢进症(简称：甲亢)和丙基硫氧嘧啶的治疗对围生儿的影响，重视甲亢治疗在改善母儿预后的作用。 方法：选取大连医科大学附属第一医院2002年01月至2011年09月妊娠合并甲状腺功能亢进症并分娩新生儿者55例进行回顾性分析，按照甲亢控制情况，服用丙基硫氧嘧啶时间进行分组，并随机选取同期正常妊娠55例为对照组，分析比较甲亢控制情况与新生儿低体重的关系，以及与新生儿黄疸的关系。 结果：1.母亲甲亢未控制组，新生儿平均出生体重低于正常分娩组和母亲甲亢控制组（P0.05）；2.母亲甲亢晚期控制组，新生儿平均出生体重低于母亲甲亢早中期控制组（P 0.05）;3.母亲甲亢未控制组，新生儿头部、胸部的平均胆红素值高于母亲甲亢控制组（P 0.05) 结论：妊娠合并甲亢及早发现，，早期系统治疗，可以有效降低新生儿LBW的发生率，降低高胆红素的发生率。
[Abstract]:Objective: to investigate the effect of hyperthyroidism and propylthiouracil on perinatal infants during pregnancy, and pay attention to the effect of hyperthyroidism therapy on maternal and fetal prognosis. Methods: from January 2002 to September 2011, 55 cases of pregnancy with hyperthyroidism and delivery of newborns in the first affiliated Hospital of Dalian Medical University were retrospectively analyzed. 55 cases of normal pregnancy were randomly selected as control group. The relationship between hyperthyroidism control and neonatal low body weight and neonatal jaundice was analyzed and compared. Results: 1. The average birth weight of the newborns was lower than that of the normal delivery group and the mother hyperthyroidism control group (P0.05). The average birth weight of newborns in the late stage control group of mother hyperthyroidism was lower than that in the early and middle period control group of maternal hyperthyroidism (P 0.05). The average bilirubin value in the head and chest of the mother with uncontrolled hyperthyroidism was higher than that in the control group of maternal hyperthyroidism (P 0.05) conclusion: pregnancy with hyperthyroidism was detected early and early systemic therapy was performed. Can effectively reduce the incidence of neonatal LBW, reduce the incidence of high bilirubin.
【学位授予单位】：大连医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R714.256;R581.1
本文编号：2340917
[Abstract]:Objective: to investigate the effect of hyperthyroidism and propylthiouracil on perinatal infants during pregnancy, and pay attention to the effect of hyperthyroidism therapy on maternal and fetal prognosis. Methods: from January 2002 to September 2011, 55 cases of pregnancy with hyperthyroidism and delivery of newborns in the first affiliated Hospital of Dalian Medical University were retrospectively analyzed. 55 cases of normal pregnancy were randomly selected as control group. The relationship between hyperthyroidism control and neonatal low body weight and neonatal jaundice was analyzed and compared. Results: 1. The average birth weight of the newborns was lower than that of the normal delivery group and the mother hyperthyroidism control group (P0.05). The average birth weight of newborns in the late stage control group of mother hyperthyroidism was lower than that in the early and middle period control group of maternal hyperthyroidism (P 0.05). The average bilirubin value in the head and chest of the mother with uncontrolled hyperthyroidism was higher than that in the control group of maternal hyperthyroidism (P 0.05) conclusion: pregnancy with hyperthyroidism was detected early and early systemic therapy was performed. Can effectively reduce the incidence of neonatal LBW, reduce the incidence of high bilirubin.
【学位授予单位】：大连医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R714.256;R581.1
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