呼吸道感染患儿病原学特点及血清肿瘤坏死因子和C-反应蛋白的诊断分析

发布时间：2018-12-12 23:47

【摘要】：目的研究呼吸道感染患儿病原学特点及血清肿瘤坏死因子(TNF-α)、C-反应蛋白(CRP)诊断运用,为临床治疗提供参考依据。方法选取医院2015年1月-2015年12月收治的544例呼吸道感染患儿,按照感染类型分为细菌感染组318例及非细菌感染组226例,并选择同期在医院健康检查的250名儿童为对照组,观察呼吸道感染患儿病原学特点及TNF-α、CRP的差异。结果感染组患儿共培养出446株病原菌,以革兰阴性菌为主,共281株占63.00%;细菌感染组血清中TNF-α及CRP水平高于非细菌感染组和对照组水平,差异有统计学意义(P0.05)。结论导致患儿呼吸道感染的病原菌相对较多,且具有季节性特点,且细菌感染的患儿血清TNF-α及CRP水平显著升高,对诊疗具有重要指导意义。
[Abstract]:Objective to study the etiological characteristics of children with respiratory tract infection and the diagnosis and application of serum tumor necrosis factor 伪 (TNF- 伪) and C-reactive protein (CRP) in order to provide reference for clinical treatment. Methods from January 2015 to December 2015, 544 children with respiratory tract infection were divided into bacterial infection group (n = 318) and non-bacterial infection group (n = 226). To observe the etiological characteristics and the difference of TNF- 伪 and CRP in children with respiratory tract infection. Results in the infection group, 446 strains of pathogenic bacteria were cultured, mainly Gram-negative bacteria, 281 strains accounted for 63.00 strains. The levels of serum TNF- 伪 and CRP in bacterial infection group were higher than those in non-bacterial infection group and control group (P0.05). Conclusion the pathogenic bacteria causing respiratory tract infection in children are relatively numerous and have seasonal characteristics. The levels of serum TNF- 伪 and CRP in children with bacterial infection are significantly increased, which is of great significance for diagnosis and treatment.
【作者单位】：西充县人民医院儿科;南充市第五人民医院骨科;南充市中心医院呼吸科;西充县人民医院体检中心;西充县人民医院检验科;
【分类号】：R725.6

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