兰州地区儿童呼吸道感染的常见病毒和肺炎支原体检测及临床分析

发布时间：2019-01-12 09:20

【摘要】：目的了解兰州地区儿童呼吸道感染常见病毒、肺炎支原体在不同季节、呼吸道疾病、年龄、性别方面的差异,为临床诊疗提供参考依据。方法对2010年4月-2011年3月间确诊为急性呼吸道感染的768例住院患儿,采用ELISA方法检测7种常见病毒的IgM抗体即：呼吸道合胞病毒(RSV)、腺病毒(ADV)、流感病毒(IFV)、副流感病毒(PIF)、艾柯病毒(ECHO)、柯萨奇病毒(COX)、 EB病毒(EBV),并对其中509例患儿标本进行肺炎支原体(MP) IgM抗体检测,并对其进行临床分析。结果768例标本中阳性检出率44.5%(342／768),其中RSV占阳性率的48.8%(167／342),以1-6月年龄组检出率最低仅为14.3%(23／161)。21例大叶性肺炎患儿进行Mp-IgM抗体检测,其中42.9%(9／21)诊断为大叶性肺炎。结论1.病毒仍是兰州地区儿童呼吸系统感染的主要病原,以RSV最为常见。2.兰州地区冬季多见ADV、 RSV感染,夏季则以EB病毒感染最常见。3.1-6月婴儿患呼吸道感染后病毒及肺炎支原体抗体检测率低。4.MP是小儿呼吸道感染的常见病原之一,也是引起大叶性肺炎的主要病原。
[Abstract]:Objective to investigate the differences of common respiratory infection virus, mycoplasma pneumoniae in different seasons, respiratory diseases, age and sex in children in Lanzhou area, so as to provide reference for clinical diagnosis and treatment. Methods from April 2010 to March 2011, 768 hospitalized children with acute respiratory tract infection were examined for IgM antibodies of seven common viruses, namely, respiratory syncytial virus (RSV), adenovirus (ADV), influenza virus (IFV),) by ELISA method. Parainfluenza virus (PIF),) (ECHO), coxsackie virus (COX), EB) (EBV), was used to detect Mycoplasma pneumoniae (MP) IgM antibody in 509 children. Results the positive rate of RSV in 768 samples was 44.5% (342 / 768), and the positive rate of RSV was 48.8% (167 / 342). The lowest detection rate was 14.3% (23 / 161) in the January to June age group. Mp-IgM antibodies were detected in 21 cases of lobar pneumonia, of which 42.9% (9 / 21) were diagnosed as lobar pneumonia. Conclusion 1. The virus is still the main cause of respiratory infection in children in Lanzhou, with RSV as the most common cause. ADV, RSV infection is more common in winter in Lanzhou area, and EB virus infection is the most common infection in summer. The detection rate of antibody to mycoplasma pneumoniae and virus after respiratory tract infection is low in infants at 3.1-6 months. 4.MP is one of the common pathogens of respiratory tract infection in children. It is also the main cause of lobar pneumonia.
【学位授予单位】：兰州大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R725.6

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