长沙市岳麓区3～5岁学龄前超重及肥胖儿童维生素D不足和缺乏的现状

发布时间：2019-03-09 15:11

【摘要】：目的:调查长沙市岳麓区3~5岁学龄前儿童维生素D(Vit D)不足与缺乏的现状,了解3~5岁学龄前儿童超重及肥胖与Vit D不足与缺乏的关联强度。方法:2015年10至12月,采用分层整群抽样法,选取岳麓区3个街道16所幼儿园的2 872名3~5岁儿童,进行体格及生化检查,对儿童家长进行问卷调查。根据其体重指数和Vit D缺乏情况,分别计算正常体型、超重及肥胖儿童的Vit D不足[血清总25(OH)D 20~30 ng/m L]率和缺乏[血清总25(OH)D20 ng/m L]率。利用多因素logistic模型,分析超重及肥胖与Vit D不足和缺乏的关联。结果:长沙3~5岁儿童Vit D不足率和缺乏率分别为39.6%(95%CI:37.8%~41.4%)和19.5%(95%CI:18.1%~21.0%);5岁儿童较4岁及以下儿童的Vit D不足率高(P0.05);补充过Vit D制剂、课外活动量5 h/周者的Vit D不足率和缺乏率较其他人群低(P0.05);牛奶饮用量越多,Vit D不足率和缺乏率越低(P0.05);3~5岁儿童超重及肥胖总患病率为19.3%(95%CI:17.8%~20.7%)。不同体型儿童Vit D不足率和缺乏率不完全相同;超重、肥胖儿童的Vit D不足率和缺乏率高于正常体型组(P0.017),分别为48.6%(95%CI:44.4%~52.9%)和24.6%(95%CI:21.1%~28.4%);在调整混杂因素的情况下,儿童超重或肥胖仍是Vit D不足和缺乏的危险因素[与Vit D不足的ORadj=1.37(95%CI:1.26~1.93);与Vit D缺乏的ORadj=1.40(95%CI:1.32~2.01)]。结论:长沙岳麓区3~5岁超重及肥胖儿童的Vit D不足率和缺乏率高于正常体型儿童,超重及肥胖儿童是Vit D缺乏干预的重点人群。
[Abstract]:Aim: to investigate the status of vitamin D (Vit D) deficiency and deficiency in preschool children aged 3-5 years old in Yuelu District of Changsha City, and to understand the relationship between overweight, obesity and Vit-D deficiency in preschool children aged 3-5 years. Methods: from October to December 2015, 2 872 3-5-year-old children from 16 kindergartens in 3 streets of Yuelu District were selected by stratified cluster sampling. Physical and biochemical examinations were carried out, and the parents of the children were investigated by questionnaire. According to body mass index (BMI) and Vit D deficiency, the rates of Vit D deficiency in normal, overweight and obese children [total serum 25 (OH) D20 ~ 30 ng/m / L] and deficiency rate [total serum 25 (OH) D20 ng/m L] were calculated. Multivariate logistic model was used to analyze the relationship between overweight and obesity and Vit D deficiency and deficiency. Results: the prevalence of Vit-D deficiency and deficiency were 39.6% (95% CI / 37.8%) and 19.5% (95% CI / 18.1% / 21.0%) in 5-year-old children in Changsha respectively. The rate of Vit-D deficiency in 5-year-old children was higher than that in 4-year-old children (P0.05), and the rate of Vit-D deficiency and deficiency in 5-hour / week extracurricular activities was lower than that in other groups (P0.05). The higher the consumption of milk, the lower the rate of, Vit D deficiency and obesity (P0.05), and the overall prevalence of overweight and obesity in 5-year-old children was 19.3% (95% CI 17.8% / 20.7%). The rates of Vit-D deficiency and deficiency in children of different somatotypes were not exactly the same. The rate of Vit-D deficiency and deficiency in overweight and obese children was higher than that in normal children (P0.017), which were 48.6% (95% CI / 44.4%) and 24.6% (95% CI / 21.1% / 28.4%), respectively. In adjusting for confounding factors, overweight or obesity was still a risk factor for Vit D deficiency and deficiency [ORadj=1.37 (95%CI:1.26~1.93) with Vit D deficiency; ORadj=1.40 (95%CI:1.32~2.01) with Vit D deficiency]. Conclusion: the Vit-D deficiency rate and deficiency rate of overweight and obesity children aged 3-5 years in Yuelu district of Changsha were higher than those of normal type children. Overweight and obesity children were the key population of Vit-D deficiency intervention.
【作者单位】：中南大学材料科学与工程学院;长沙市岳麓区妇幼保健所;湖南师范大学医学院预防医学系;
【基金】：湖南省自然科学基金(2017JJ3215) 湖南省教育厅科学研究项目(17C0961)~~
【分类号】：R723.14

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