亳州地区2846例儿童急性呼吸道感染病原体IgM抗体检测结果分析

发布时间：2019-03-31 18:24

【摘要】：目的了解亳州地区儿童急性呼吸道感染病例病原体的分布情况。方法采用间接免疫荧光法对该院2015年4月至2016年3月诊治的2 846例急性呼吸道感染患儿外周血标本进行腺病毒、流感病毒A、流感病毒B、呼吸道合胞病毒、副流感病毒、肺炎支原体、肺炎衣原体、嗜肺军团菌检测,了解患儿病原体的分布情况。结果 2 846例患儿病原体检测阳性1 161例(40.8%),其中检出率最高的前3位病原体分别是肺炎支原体[470例(16.5%)]、流感病毒A[252例(8.9%)]及呼吸道合胞病毒[117例(4.1%)],并有79例混合感染(2.8%)。随年龄增加病原体检出率呈下降趋势(χ~2=20.724,P=0.000 1)。婴幼儿感染以呼吸道合胞病毒为主(11.2%),学龄前及学龄儿童以肺炎支原体感染为主(15.2%~25.4%)。冬季病原体感染检出率最高(57.7%),夏季最低(22.5%)。结论亳州地区急性呼吸道感染病原体流行病学分布随年龄、季节而不同,婴幼儿感染率高于其他年龄段,肺炎支原体、流感病毒A及呼吸道合胞病毒是亳州地区儿童急性呼吸道感染的主要病原体,秋冬季高发应注意加强预防感染。
[Abstract]:Objective to investigate the distribution of pathogens in children with acute respiratory tract infection (ARI) in Bozhou. Methods adenovirus, influenza A, influenza B, respiratory syncytial virus and parainfluenza virus were detected by indirect immunofluorescence in peripheral blood samples of 2846 children with acute respiratory tract infection from April 2015 to March 2016. Mycoplasma pneumoniae, Chlamydia pneumoniae, Legionella pneumophila detection, to understand the distribution of pathogens in children. Results 1 161 cases (40.8%) were positive for pathogen detection in 2 846 cases, among which the first 3 pathogens were Mycoplasma pneumoniae [470 cases (16.5%)], and the highest positive rate was mycoplasma pneumoniae [470 cases (16.5%)]. Influenza virus A [252 cases (8.9%)] and respiratory syncytial virus [117 cases (4.1%)], and 79 cases of mixed infection (2.8%). The detection rate of pathogens decreased with age (蠂 ~ 2, 20.724, P < 0.0001). Respiratory syncytial virus was the main infection in infants (11.2%), Mycoplasma pneumoniae infection was predominant in preschool and school-age children (15.2% / 25.4%). The detection rate of pathogen infection was the highest (57.7%) in winter and the lowest (22.5%) in summer. Conclusion the distribution of pathogens of acute respiratory tract infection varies with age and season in Bozhou. The infection rate of infants is higher than that of mycoplasma pneumoniae in other age groups. Influenza virus A and respiratory syncytial virus are the main pathogens of acute respiratory tract infection in Bozhou area. The high incidence of influenza A and respiratory syncytial virus in autumn and winter should be strengthened to prevent infection.
【作者单位】：安徽省亳州市人民医院儿科;
【分类号】：R725.6

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