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早产儿出生时血清25-羟维生素D水平与支气管肺发育不良的相关性

发布时间:2019-05-12 19:40
【摘要】:目的分析早产儿出生时血清25-羟维生素D[25(OH)D]水平与支气管肺发育不良(BPD)的关系。方法选取2014年1月至2016年12月入住NICU、出生胎龄34周的早产儿,按是否患BPD分为BPD组(41例)和对照组(219例),分析25(OH)D水平与BPD的关系。结果 BPD组血清25(OH)D水平显著低于对照组(37±17 nmol/L vs 47±20 nmol/L;P0.05);维生素D缺乏率显著高于对照组(90.2%vs 74.0%,P0.05)。血清25(OH)D水平与BPD发生率呈负相关(r=-0.201,P=0.001)。结论早产儿维生素D缺乏可能与BPD发病有关,但需多因素分析进一步证实。
[Abstract]:Objective to analyze the relationship between serum 25-hydroxyvitamin D [25 (OH) D] and (BPD) in premature infants. Methods from January 2014 to December 2016, preterm infants with 34 weeks of gestational age in NICU, were divided into BPD group (n = 41) and control group (n = 219) according to whether they had BPD or not. The relationship between 25 (OH) D level and BPD was analyzed. Results the level of serum 25 (OH) D in BPD group was significantly lower than that in control group (37 卤17 nmol/L vs 47 卤20 nmol/L;P0.05), and the vitamin D deficiency rate was significantly higher than that in control group (90.2%vs 74.0%, P0.05). The level of serum 25 (OH) D was negatively correlated with the incidence of BPD (r 鈮,

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