小儿急性肠系膜淋巴结炎44例病原学检测分析

发布时间：2019-05-14 07:27

【摘要】：目的了解引起小儿急性肠系膜淋巴结炎的病原学情况。方法 (1)收集44例小儿急性肠系膜淋巴结炎患儿的血清标本,采用蛋白芯片技术同时检测肺炎衣原体(CPn)、肺炎支原体(MP)、呼吸道合胞病毒(RSV)、腺病毒(ADV)、流感病毒(IFA)、副流感病毒(PIV)的抗体。(2)采用胶体金法对部分患儿行柯萨奇病毒CA16型、肠道病毒71型Ig M抗体的检测。结果 (1)44例患儿检出病原25例,总阳性率56.8%,其中IFA检出率为80%(20/25),MP为48%(12/25),ADV为44%(11/25)。72%(18/25)为混合感染,其中IFA+ADV感染检出率最高,占混合感染的44%(8/18)。(2)21例患儿胶体金法检测柯萨奇病毒CA16型与肠道病毒71型均为阴性。结论 (1)引起小儿急性肠系膜淋巴结炎病原以呼吸道感染常见病原体如IFA、ADV、MP为主,且大多数是混合感染,以IFA+ADV最常见。(2)蛋白芯片技术操作简单,且能同时检测多种病原体,提高了效率,降低了成本。
[Abstract]:Objective to investigate the etiology of acute mesenteric lymphadenitis in children. Methods (1) the serum samples of 44 children with acute mesenteric lymphadenitis were collected. Chlamydia pneumoniae (CPn), Mycoplasma pneumoniae (MP), respiratory syncytial virus (RSV), adenoviral (ADV), was detected by protein chip technique. Antibody to influenza virus (IFA), parainfluenza virus (PIV). (2) Colloidal gold method was used to detect Coxsackie virus CA16 and enterovirus 71 Ig M antibody in some children. Results (1) 25 cases of pathogen were detected in 44 children, the total positive rate was 56.8%, of which the detection rate of IFA was 80% (20 鈮，

本文编号：2476531