氨溴索不同给药途径治疗小儿呼吸系统疾病的疗效比较

发布时间：2019-07-16 07:25

【摘要】：目的:探讨氨溴索治疗小儿呼吸系统疾病的最佳给药途径。方法:选择2014年6月-2016年6月我院儿科收治的呼吸系统疾病患儿120例,按就诊单双号顺序分为静脉滴注组和雾化吸入组,各60例。在常规治疗基础上,静脉滴注组患儿给予盐酸氨溴索注射液7.5 mg溶入50 m L 5%葡萄糖注射液中,ivgtt,bid;雾化吸入组患儿雾化吸入盐酸氨溴索注射液7.5 mg,每次吸入15min,bid。两组患儿均治疗7 d。比较两组患儿的临床疗效,氧分压[p(O_2)]、二氧化碳分压[p(CO_2)]、吸痰次数、临床指标和不良反应发生情况。结果:雾化吸入组患儿的总有效率(96.67%)显著高于静脉滴注组(78.33%),p(O_2)水平显著高于静脉滴注组,吸痰次数显著少于静脉滴注组,发热消失时间、气喘消失时间、氧疗时间、肺部Up音消失时间、咳嗽消失时间和平均住院时间均显著短于静脉滴注组,差异均有统计学意义(P0.05)。两组患儿的p(CO_2)水平和不良反应发生率比较,差异均无统计学意义(P0.05)。结论:氨溴索能有效治疗小儿呼吸系统疾病,且雾化吸入的临床疗效优于静脉滴注。
[Abstract]:Objective: to explore the best administration of ambroxol in the treatment of respiratory diseases in children. Methods: from June 2014 to June 2016, 120 children with respiratory diseases were divided into intravenous drip group (n = 60) and atomization inhalation group (n = 60). On the basis of routine treatment, the children in the intravenous drip group were given ambroxol hydrochloric acid injection 7.5 mg and dissolved into 50 mL 5% glucose injection. The children in the ivgtt,bid; atomization inhalation group inhaled ambroxol hydrochloric acid injection 7.5 mg, each time for 15 min. The children in both groups were treated for 7 days. The clinical efficacy, partial pressure of oxygen [p (O 鈮，

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