手足口病病毒抗体喷剂对小儿手足口病的疗效

发布时间：2019-07-31 16:26

【摘要】：目的探讨手足口病病毒抗体喷剂对小儿手足口病的疗效。方法选取258例轻型小儿手足口病患儿,按治疗方法差异分为研究组(129例)和对照组(129例)。两组患儿均予以安慰剂治疗及退热等对症治疗,研究组在此基础上再给予手足口病病毒抗体喷剂直接喷口腔疱疹、溃疡,外喷皮疹,观察和记录两组的症状改善情况及疗效。结果研究组体温恢复正常、进食改善至正常、口腔疱疹愈合、手足皮疹消退、白细胞恢复正常时间均明显短于对照组,差异均有统计学意义(P0.05)。研究组的临床总有效率为94.5%,明显高于对照组的79.8%,且研究组不良反应发生率为0,明显低于对照组6.8%,差异有统计学意义(P0.05)。结论手足口病病毒抗体喷剂治疗轻型小儿手足口病,有利于改善症状,加速口腔疱疹溃疡愈合、皮疹消退,缩短病程,疗效显著。
[Abstract]:Objective to investigate the efficacy of hand, foot and mouth disease virus antibody spray in the treatment of hand, foot and mouth disease in children. Methods 258 children with mild HFMD were divided into study group (129 cases) and control group (129 cases) according to the difference of treatment methods. Both groups were treated with placebo and antipyretic therapy. On this basis, the study group was given hand, foot and mouth disease virus antibody spray directly spray oral herpes, ulcer, external spray rash, observe and record the symptom improvement and curative effect of the two groups. Results the body temperature of the study group returned to normal, eating improved to normal, oral herpes healed, hand and foot rash disappeared, leukocyte recovery time was significantly shorter than that of the control group, the difference was statistically significant (P 0.05). The total clinical effective rate of the study group was 94.5%, which was significantly higher than that of the control group (79.8%), and the incidence of adverse reactions in the study group was 0, which was significantly lower than that of the control group (6.8%) (P 0.05). Conclusion hand, foot and mouth disease virus antibody spray in the treatment of mild hand, foot and mouth disease is beneficial to improve the symptoms, accelerate the healing of oral herpes ulcer, rash regression, shorten the course of disease, the curative effect is remarkable.
【作者单位】：益阳市第四人民医院儿童医学中心;
【分类号】：R725.1

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