上髓帆位置的改变在小脑中线髓母细胞瘤与星形细胞瘤鉴别诊断中的应用价值

发布时间：2018-01-29 16:17

本文关键词： 上髓帆髓母细胞瘤星形细胞瘤　出处：《临床放射学杂志》2015年08期 　论文类型：期刊论文

【摘要】：目的探讨上髓帆位置的改变在小脑中线髓母细胞瘤和星形细胞瘤鉴别诊断中的应用价值。方法搜集经手术病理证实的29例小脑中线髓母细胞瘤和星形细胞瘤患儿的MRI资料,其中髓母细胞瘤21例,星形细胞瘤8例。观察不同肿瘤正中矢状位上髓帆的位置;测量不同肿瘤上髓帆与前颅底水平线的夹角,并绘制ROC曲线;预测小脑中线髓母细胞瘤与星形细胞瘤鉴别诊断的最佳角度。结果髓母细胞瘤组19例患儿上髓帆向上移位,1例向前移位,1例上髓帆位置无异常;星形细胞瘤组6例患儿上髓帆向前/向下移位,2例向上移位;髓母细胞瘤上髓帆与前颅底水平线的夹角平均值为(130.8±23.5)°,小脑中线星形细胞瘤上髓帆与前颅底水平线的夹角为(99.2±18.2)°,小脑中线髓母细胞瘤鉴别星形细胞瘤时上髓帆与前颅底水平线的最佳角度为115°。结论肿瘤正中矢状位上髓帆位置的改变可用于儿童小脑中线髓母细胞瘤和星形细胞瘤的鉴别诊断;上髓帆与前颅底水平线夹角115°时,诊断为髓母细胞瘤的准确性较高。
[Abstract]:Objective to investigate the value of the change of upper medullary sail position in differential diagnosis of cerebellar midline medulloblastoma and astrocytoma. Methods 29 cases of cerebellar midline medulloblastoma and astrocytoma confirmed by surgery and pathology were collected. Son's MRI data. There were 21 cases of medulloblastoma and 8 cases of astrocytoma. The angle between the medullary sail and the anterior skull base was measured and the ROC curve was drawn. The best angle of differential diagnosis between medulloblastoma and astrocytoma was predicted. Results in 19 cases of medulloblastoma, the upper medullary sail was shifted upward in 1 case and the upper medullary sail was not abnormal in 1 case. In the astrocytoma group, the upper medullary sail was shifted forward / downward in 6 cases and upward in 2 cases. The mean angle between the upper medullary sail and the anterior skull base was 130.8 卤23.5 掳. The angle between the upper medullary sail of cerebellar midline astrocytoma and the horizontal line of anterior skull base was 99.2 卤18.2 掳. The optimal angle for differentiating medulloblastoma from anterior skull base is 115 掳. Conclusion the change of the location of the medulloblae in the median sagittal position of the tumor can be used in the diagnosis of cerebellar midline medulloblastoma and cerebellar midline medulloblastoma in children. Differential diagnosis of astrocytoma; The accuracy of diagnosis of medulloblastoma was higher when the angle between upper medullary sail and anterior skull base was 115 掳.
【作者单位】：郑州大学第一附属医院磁共振科;
【分类号】：R739.4;R445.2
【正文快照】： 髓母细胞瘤是儿童神经系统最常见的肿瘤[1],比小脑星形细胞瘤稍多见。手术前正确诊断肿瘤的类型对治疗方案的制定具有重要的意义,常规MR成像技术和MR成像新技术都可以用于术前两种肿瘤的鉴别[2~4]。但并不是所有的医院都具备开展MR新技术(如MRS或DWI)的条件,而且新技术的

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