甲状腺微小乳头状癌被膜外侵犯的超声评估

发布时间：2018-02-04 17:32

本文关键词： 甲状腺微小癌超声检查被膜侵犯　出处：《中国超声医学杂志》2017年07期 　论文类型：期刊论文

【摘要】：目的探讨超声征象对甲状腺微小乳头状癌(PTMC)被膜外侵犯的预测能力。方法收集经手术治疗的PTMC患者62例,共77个结节,根据术后病理将患者分为无被膜外侵犯组(non-ETE)和有被膜外侵犯(ETE)组。回顾分析声像图特点,探讨其预测PTMC存在被膜外侵犯的能力。结果 non-ETE组43例、55(71.43%)个结节,ETE组19例、22(28.57%)个结节。结节紧邻甲状腺被膜在non-ETE组(8/55)和ETE组(19/22)比较差异有统计学意义(P=0.000),该超声征象诊断PTMC存在被膜外侵犯的灵敏度、特异度、准确度、阳性预测值、阴性预测值分别为94.00%、70.37%、85.71%、85.45%和86.36%。甲状腺被膜连续性中断或消失在non-ETE组(3/55)和ETE组(15/22)比较,差异亦有显著统计学意义(P=0.000),其诊断PTMC存在被膜外侵犯的灵敏度、特异度、准确度、阳性预测值、阴性预测值分别为83.33%、88.14%、87.01%、68.18%和94.55%。上述两项超声指标联合诊断PTMC存在被膜外侵犯的ROC曲线下面积为0.885(0.790~0.981)。结论应用超声观察结节与甲状腺被膜的关系以及被膜的完整性对判断PTMC是否存在被膜外侵犯具有重要价值。
[Abstract]:Objective to investigate the predictive ability of ultrasound signs for extramembranous invasion of thyroid micropapillary carcinoma (PTMC). Methods Sixty-two patients with PTMC underwent surgical treatment and 77 nodules were collected. According to the postoperative pathology, the patients were divided into two groups: the non-ETEG group and the ETEG group. The ultrasonographic features were analyzed retrospectively. Results in the non-ETE group, 43 cases were diagnosed as 5571.43 and 19 cases in the non-ETE group. The number of nodules adjacent to the thyroid capsule in the non-ETE group was 8 / 55) and that in the ETE group was 19 / 22). There was significant difference between the two groups (P < 0. 000). The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of PTMC were 94.00%, 70.37% and 85.71%, respectively. 85.45% and 86.36. The continuity of thyroid capsule was interrupted or disappeared in non-ETE group (3 / 55) and ETE group (15 / 22). The difference was also statistically significant. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of PTMC were 83.33%, respectively. 88.14%, 87.01%. 68.18% and 94.55.The area under the ROC curve for the diagnosis of extramembranous invasion of PTMC was 0.885v 0.790 / 0.981). Conclusion it is important to observe the relationship between the nodular and thyroid capsule and the integrity of the capsule to determine the existence of extramembranous invasion of PTMC.
【作者单位】：重庆市肿瘤研究所/医院/癌症中心超声医学科;
【基金】：重庆市卫生计生委科研面上项目(No.2015MSXM225)
【分类号】：R445.1;R736.1
【正文快照】： 作者单位:400030重庆市,重庆市肿瘤研究所/医院/癌症中心超声医学科结果non-ETE组43例、55(71.43%)个结节,ETE组19例、22(28.57%)个结节。结节紧邻甲状腺被膜在non-ETE组(8/55)和ETE组(19/22)比较差异有统计学意义(P=0.000),该超声征象诊断PTMC存在被膜外侵犯的灵敏度、特异度

【参考文献】