剪切波弹性成像评估原发性肝细胞癌手术范围

发布时间：2018-02-11 21:57

本文关键词： 弹性成像技术癌肝细胞手术范围　出处：《中国医学影像技术》2015年05期 　论文类型：期刊论文

【摘要】：目的探讨实时剪切波弹性成像(SWE)技术在原发性肝细胞癌(HCC)手术范围评估中的临床应用价值。方法回顾性分析45例经术后病理检查证实为HCC患者的SWE声像图资料。对比HCC病灶,距病灶1、2、3cm肝组织及正常肝组织的弹性模量值,并进行统计学分析。结果 HCC病灶,距病灶1、2、3cm肝组织及正常肝组织弹性模量的平均值分别为(28.19±6.14)kPa、(17.14±5.34)kPa、(13.44±3.76)kPa、(10.98±3.44)kPa及(10.03±3.69)kPa。HCC病灶,距病灶1、2cm肝组织与距病灶3cm肝组织及正常肝组织间差异均有统计学意义(P均0.05);距病灶1cm肝组织与距病灶2cm肝组织间差异有统计学意义(P0.05);距病灶3cm肝组织与正常组织间差异无统计学意义(P0.05)。2名医师对HCC病灶,距病灶1、3cm肝组织及正常肝组织所测弹性模量值差异均无统计学意义(P均0.05),仅对距病灶2cm肝组织弹性模量值差异有统计学意义(P=0.02)。结论采用SWE技术测定HCC病灶及其周边不同范围肝组织的弹性模量值可为术前评估手术切缘范围提供参考信息。
[Abstract]:Objective to evaluate the clinical value of real time shear wave elastography (SWE) in evaluating the operative range of primary hepatocellular carcinoma (HCC). Methods the sonographic data of 45 patients with HCC proved by pathological examination after operation were retrospectively analyzed and compared with the focus of HCC. Results the mean values of elastic modulus of liver tissue and normal liver tissue in HCC were 28.19 卤6.14 ~ 6.14 卤5.34 卤5.34 KPA 10.98 卤3.44 KPA and 10.03 卤3.69 KPA, respectively, and were 13.44 卤3.44 卤3.44 卤3.44 KPA, 10.03 卤3.69 KPA, respectively, and the mean values of elastic modulus in normal liver tissue and normal liver tissue were 13.44 卤3.76kPa10.98 卤3.44kPa and 10.03 卤3.69kPa.HCC, respectively, with a mean value of 17.14 卤5.34 KPA, 13.44 卤3.76kPa10.98 卤3.44kPa, and 10.03 卤3.69kPa.HCC, respectively. There were significant differences between liver tissue (1cm to focus), liver tissue (3cm from lesion) and normal liver tissue (P 0.05), between liver tissue (1cm from focus) and liver tissue (2cm from lesion), between liver tissue (3cm from lesion) and normal liver tissue (P < 0.05). There was no statistically significant difference in tissue between two groups (P0.05. 2) for HCC lesions. There was no significant difference in elastic modulus between 1 ~ 3 cm liver tissue and normal liver tissue (P < 0.05), but there was significant difference in elastic modulus value between liver tissue of 2 cm away from focus. Conclusion SWE technique is used to measure HCC lesion and its periphery. The elastic modulus of liver tissue in different range of side can provide reference information for preoperative evaluation of the margin of operation.
【作者单位】：中国医科大学附属第一医院超声科;
【分类号】：R735.7;R445.1

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