磁共振IVIM技术临床应用稳定性分析

发布时间：2018-02-16 18:38

本文关键词： 磁共振 IVIM 变异系数　出处：《临床放射学杂志》2017年08期 　论文类型：期刊论文

【摘要】：目的探讨体素内不相干运动扩散加权成像(IVIM-DWI)技术在不同部位应用的稳定性。方法分别对60例患者包括20例正常表现脑、肝脏及女性盆腔进行3.0 T GE磁共振8b值DWI序列扫描,使用工作站计算相关参数包括慢速ADC(D)、快速ADC(D~*)、灌注相关体积分数ADC(f),每个部位选取3个观测点,脑区包括右侧额叶脑灰质、白质及基底节,肝脏为肝脏顶部、左叶及右叶,盆腔为子宫体肌、臀肌、髂骨骨髓,放置感兴趣区测量,分别计算比较各观测点的D、D~*、f值的变异系数。结果各部位D、D~*、f值变异系数分别为:脑白质0.081、0.299、0.341;脑灰质0.092、0.292、0.297;基底节0.098、0.573、0.333;肝顶0.277、0.545、0.382;肝右叶0.324、0.553、0.352;肝左叶0.367、0.499、0.258;子宫肌壁0.096、0.629、0.197;盆腔肌肉0.101、0.945、0.95;髂骨髓腔0.19、0.481、0.365。9个测量点中D值的变异系数在三个参数中相对较低;三个部位中,脑组织3个观察点的D值及D~*值变异系数较低。结论脑组织的IVIM技术总体应用的稳定性优于盆腔及肝脏;各部位IVIM相关参数中,D值的稳定性好于D~*及f。
[Abstract]:Objective to investigate the stability of IVIM-DWI in 60 patients, including 20 cases of normal brain, liver and female pelvic cavity, and to evaluate the stability of IVIM-DWI. Methods the 30-T GE MRI 8b DWI sequence was performed in 60 patients, including 20 patients with normal brain, liver and female pelvic cavity. The parameters calculated by workstation included slow ADCD, rapid ADCD, perfusion related volume fraction (ADCF), three observation points were selected for each site. The brain region included the right frontal lobe gray matter, white matter and basal ganglia, liver as the top of the liver, Zuo Ye and right lobe. Pelvic muscles, gluteal muscles, bone marrow of ilium were measured by placing the area of interest. Results the coefficients of variation were 0.081-0.2990.341 in the white matter of the brain, 0.292 in the gray matter of the brain, 0.0980.5730.333in the basal ganglia, 0.2770.540.545a 0.382 in the top of the liver, 0.3240.5530.352in the right lobe of the liver, 0.49999.258in the right lobe, 0.0966o0.629290.197 in the uterine muscle wall, 0.1010.940.95in the pelvic muscle, 0.1012940.95in the pelvic muscle, 0.1010.4940.95in the pelvic muscle, and 0.3240.5530.352in the right lobe of the liver, respectively. The coefficient of variation of D value in 0.19 ~ 0.481,0.365.9 measured points was relatively low in the three parameters. Among the three sites, the D value and D * value of brain tissue were low. Conclusion the stability of IVIM technique in brain tissue is better than that in pelvic cavity and liver, and the stability of D value in IVIM related parameters is better than that in DX * and f.
【作者单位】：郑州大学附属肿瘤医院放射科;
【基金】：2014河南省科技厅计划项目(编号:142102310435)基金资助项目
【分类号】：R445.2

【参考文献】