经直肠剪切波弹性成像对前列腺癌诊断价值的Meta分析

发布时间：2018-02-23 12:40

本文关键词： 剪切波弹性成像技术前列腺肿瘤活组织检测 Meta分析　出处：《中国介入影像与治疗学》2017年08期 　论文类型：期刊论文

【摘要】：目的采用Meta分析评价经直肠剪切波弹性成像在前列腺癌诊断中的应用价值。方法检索2016年12月以前有关经直肠剪切波弹性成像诊断前列腺癌的中、英文文献,按照诊断性试验的纳入标准筛选文献,采用Meta-Disc 1.4及Stata 12.0软件对纳入的文献进行Meta分析。结果共纳入8篇文献,其中经直肠剪切波弹性成像诊断前列腺癌的研究有5篇,汇总分析后,其诊断前列腺癌的合并敏感度(SEN)为0.80[95%CI(0.75,0.84)],合并特异度(SPE)为0.75[95%CI(0.71,0.79)],阳性似然比(PLR)为3.60[95%CI(2.57,5.05)],阴性似然比(NLR)为0.17[95%CI(0.08,0.37)],SROC曲线下面积(AUC)为0.895。经直肠剪切波弹性成像辅助下穿刺诊断前列腺癌的研究亦是5篇,汇总分析后,其合并SEN为0.86[95%CI(0.83,0.88)],SPE为0.84[95%CI(0.82,0.85)],PLR为5.81[95%CI(3.07,10.99)],NLR为0.14[95%CI(0.04,0.49)],SROC曲线下面积(AUC)为0.924。结论经直肠剪切波弹性成像在前列腺癌诊断中有较好临床应用价值,且可作为经直肠超声引导下前列腺穿刺的辅助方法。
[Abstract]:Objective to evaluate the value of transrectal shear wave elastography in the diagnosis of prostate cancer by Meta analysis. According to the inclusion criteria of diagnostic test, Meta analysis was carried out by using Meta-Disc 1.4 and Stata 12.0 software. Results eight articles were included, including 5 studies on the diagnosis of prostate cancer by transrectal shear wave elastography. After summing up the analysis, The diagnostic sensitivity for prostate cancer was 0.80 (95CI0.750.84), the combined specificity was 0.75 (95CI0.71U 0.79), the positive likelihood ratio (PLR) was 3.60 [95CIN 2.570.05], the negative likelihood ratio (NLR) was 0.17 [95CIR = 0.080.37)] the area under SROC curve was 0.895.The area under SROC curve was 0.895.The area under SROC curve was 0.895.The positive likelihood ratio (PLR) was 3.60 [95CIT 2.57V 5.05], and the negative likelihood ratio (NLR) was 0.17 [95CI0.85 卤0.37] SROC curve (AUC) was 0.895.The area under SROC curve was 0.895.The positive likelihood ratio (PLR) was 3.60 [95CII 2.57U 5.05]. The combined SEN was 0.86 [95CIJ 0.83U 0.88] and the SEN was 0.84 [95CI0.82U 0.85] SEN was 5.81 [95CII 3.070.99] NLR was 0.14 [95CI0.040.49] SEN was 0.924.Conclusion rectal shear wave elastography has a better clinical value in the diagnosis of prostate cancer. It can be used as an assistant method of prostate puncture guided by transrectal ultrasound.
【作者单位】：兰州大学第二医院超声3科;
【分类号】：R445.1;R737.25

【参考文献】