高分辨MRI对大脑中动脉粥样硬化斑块分布特点及稳定性的研究

发布时间：2018-03-08 08:02

本文选题：高分辨磁共振成像　切入点：大脑中动脉　出处：《临床放射学杂志》2017年02期 　论文类型：期刊论文

【摘要】：目的通过高分辨MRI(HR-MRI)探讨大脑中动脉粥样硬化斑块的分布特点及斑块性质。方法前瞻性纳入经颅脑MRA检查证实大脑中动脉M1段有粥样硬化斑块的患者52例,所有病例均为单侧发病。依据DWI及临床表现分为症状性组(27例)和非症状性组(25例),对大脑中动脉动脉粥样硬化斑块处行HR-MRI扫描。结果症状性组27例,21例为易损性斑块;非症状性组25例,11例为易损性斑块。两组比较易损性斑块的发生率差异有统计学意义(P=0.012)。症状性组斑块最大厚度为(1.80±0.33)mm,非症状性组斑块最大厚度为(1.51±0.37)mm,两组比较差异有统计学意义(P=0.004)。大脑中动脉粥样硬化斑块易发生于管腔前壁(22/52),其次为管腔下壁(13/52)。单因素分析症状性组与非症状性组斑块分布部位的差异无统计学意义(P0.05)。结论HR-MRI可有效的对大脑中动脉粥样硬化斑块进行定位、定量、定性分析,为临床诊断及治疗提供影像依据。
[Abstract]:Objective to investigate the distribution and character of atherosclerotic plaques in middle cerebral artery (MCAA) by high resolution MRI HR-MRI. Methods 52 patients with atherosclerotic plaques at M1 segment of middle cerebral artery were prospectively included in this study. According to DWI and clinical manifestations, all cases were divided into symptomatic group (n = 27) and non-symptomatic group (n = 25). HR-MRI scanning was performed on atherosclerotic plaques of middle cerebral artery (MCAA). There was a significant difference in the incidence of vulnerable plaques between the two groups. The maximum thickness of plaque in symptomatic group was 1.80 卤0.33 mm, and that in non-symptomatic group was 1.51 卤0.37 mm. There was a significant difference between the two groups. Atherosclerotic plaques in the middle cerebral artery were more likely to occur in the anterior wall of the lumen than in the anterior wall of the lumen, followed by the inferior wall of the lumen. There was no significant difference in the distribution of plaques between symptomatic and nonsymptomatic groups by univariate analysis (P 0.05). Conclusion HR-MRI may have a positive effect on the distribution of plaques in the anterior wall of the lumen. To locate atherosclerotic plaques in the middle cerebral artery, Quantitative and qualitative analysis provide imaging basis for clinical diagnosis and treatment.
【作者单位】：河北省沧州市人民医院放射科;
【分类号】：R743.3;R445.2

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