超声造影评价颈动脉斑块类型与斑块内新生血管关系

发布时间：2018-03-19 22:19

本文选题：超声检查　切入点：造影剂　出处：《中国医学影像技术》2015年01期 　论文类型：期刊论文

【摘要】：目的采用灰阶谐波CEUS评价斑块内新生血管与常规超声显示斑块类型之间的关系。方法收集98例颈动脉粥样硬化患者共113个斑块,根据回声特征及形态学分为均质、非均质及溃疡型斑块,均质斑块又分为低回声、等回声及强回声斑块。分析斑块回声特征与造影增强模式特点。结果 CEUS显示低回声斑块新生血管检出率明显高于等回声(χ2=10.64,P=0.001)、强回声(χ2=18.62,P0.001)及溃疡型斑块(χ2=7.38,P=0.007);但低回声与非均质斑块新生血管检出率的差异无统计学意义(χ2=2.20,P=0.138)。增强的64个斑块中,46个(46/64,71.88%)斑块表现为由管壁外膜向斑块内增强,其中44个弥漫性增强,2个为束状增强;18个(18/64,28.13%)斑块表现为由管腔向斑块内蔓延的稀疏增强。各类型斑块间CEUS增强模式的差异无统计学意义(P0.05)。结论 CEUS可提供更多有关于斑块内新生血管的信息,有助于进一步判断斑块稳定性。
[Abstract]:Objective to evaluate the relationship between intraplaque neovascularization and plaque type by conventional ultrasound using gray scale harmonic CEUS. Methods 113 plaques were collected from 98 patients with carotid atherosclerosis. Heterogeneous and ulcerative plaques were divided into hypoechoic plaques. Isoechoic and hyperechoic plaques. The characteristics of echo and enhancement pattern of plaque were analyzed. Results CEUS showed that the detection rate of neovascularization in hypoechoic plaques was significantly higher than that in isoechoic plaques (蠂 ~ 2 ~ 2 ~ (10.64) P ~ (0.001), P ~ (0.001)) and ulcerative plaques (蠂 ~ (2) ~ (7.38) P ~ (0.007)), but hypoechoic and hyperechoic plaques (P ~ (0.007)). There was no significant difference in the detection rate of angiogenesis in heterogeneous plaques (蠂 ~ 2 / 2.20) (蠂 ~ 2 / 2.20) (0.138%). Of the 64 plaques enhanced, 46% (46 / 64) showed enhancement from the outer membrane of the wall to the plaque (71.88%). Among them, 44 diffuse enhancement, 2 bundle enhancement and 18 18 / 644 / 28.13 plaques showed sparse enhancement from lumen to plaque. There was no significant difference in CEUS enhancement pattern between different types of plaques (P 0.05). Conclusion CEUS can provide more information. Information on intraplaque angiogenesis, It is helpful to judge the stability of plaque.
【作者单位】：宁夏医科大学总医院超声科;
【基金】：宁夏自治区科技攻关项目
【分类号】：R543.4;R445.1

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