早中孕期颅脑冠状切面鼻尖偏斜法用于胎儿颜面部筛查的相关研究

发布时间：2018-03-20 00:11

本文选题：颅脑冠状切面鼻尖偏斜法　切入点：早中孕期　出处：《实用医学杂志》2017年18期 　论文类型：期刊论文

【摘要】：目的探讨早中孕期颅脑冠状切面鼻尖偏斜法在筛查胎儿颜面部畸形中的临床价值。方法采用颅脑冠状切面鼻尖偏斜法超声检查,对5 000例早中孕期孕妇的胎儿进行颜面部结构检查。根据进行超声检查的时间,分为11～12~(+6)周组、13～14~(+6)周组、15～16~(+6)周组。分析胎儿颜面部结构显示情况以及胎儿畸形检出率。结果所有孕妇超声检查均可以清楚显示颅脑冠状切面,其中4 855例(97.10%)可见较为理想的小脑横切面、双眼球水平冠状切面、鼻后三角切面等。三组胎儿超声检查显示率没有统计学差异。有69例(1.38%)出现颜面部畸形,其中31例(44.93%)为单纯颜面部畸形,38例(55.07%)合并其他结构畸形。该方法的敏感度、特异性、阳性预测值、阴性预测值分别为93.24%,100%,100%,99.90%。结论颅脑冠状切面鼻尖偏斜法对胎儿颜面部畸形的检出率和灵敏度较高是中早孕期胎儿颜面部排畸检查的可靠方法。
[Abstract]:Objective to investigate the clinical value of craniocerebral coronal section nasal tip deflection in screening fetal facial malformation. Facial structure was examined in 5,000 fetuses of pregnant women during early and middle pregnancy. According to the time of ultrasound examination, The fetal facial structure and the detection rate of fetal malformation were analyzed. Results all the pregnant women could clearly display the coronal section of the brain by ultrasound, and were divided into two groups: one week, one week, one week, one week, one week, one week, one week, one week, one week, one week, one week. Among them, 4 855 cases (97. 10) could be seen on the transverse plane of cerebellum, horizontal coronal section of double eyeball, posterior triangulation of nose and so on. There was no statistical difference in the rate of fetal ultrasound examination among the three groups. 69 cases (1. 38) had facial deformity. Among them, 31 cases (44.93) were simple facial deformities (38 cases) combined with other structural deformities, the sensitivity, specificity, positive predictive value of this method, The negative predictive values were 93.24 / 100 and 99.900.Conclusion the detection rate and sensitivity of craniocerebral coronal section nasal tip deflection method for fetal facial deformity is a reliable method for the examination of fetal facial drainage in middle and early pregnancy.
【作者单位】：重庆开州区人民医院超声科;
【基金】：重庆市卫生计生委2016年医学科研计划项目(编号:2016MSXM194)
【分类号】：R445.1;R714.5

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