成人幕上原始神经外胚层肿瘤的MRI表现及病理特点分析

发布时间：2018-03-25 20:14

本文选题：成人　切入点：幕上　出处：《临床放射学杂志》2015年05期

【摘要】：目的探讨成人幕上原始神经外胚层肿瘤(SPNET)的MRI表现与病理联系,提高诊断水平。方法搜集10例经手术病理证实的成人SPNET的临床病理及MRI资料,回顾性分析其影像学特点,并结合病理归纳其联系。男女比例为7∶3,中位年龄45.0岁,7例以头痛、呕吐首发,2例头痛伴晕厥,1例面部及舌根部麻木。均采用GE 1.5 T MRI扫描仪行MRI平扫+增强检查。结果病灶均单发,其中额叶5例、颞叶3例、顶叶2例,1例累及胼胝体膝部,无一例术前发生转移。病灶体积大,边界清,占位效应显著,3例无水肿,5例伴轻度水肿,2例伴明显水肿,2例伴出血,未见钙化。囊实性为主6例,表现为大囊小结节,壁结节多位于大脑凸面,囊变常靠近中线,实性为主4例,可伴灶性坏死,MRI上呈等或低T1WI、高或稍高T2WI信号,增强后呈"印戒"样或"蜂窝"样强化。结论成人SPNET的MRI表现与组织学特点密切相关,MRI表现具有特征性,仍依靠病理学确诊。
[Abstract]:Objective to investigate the relationship between MRI findings and pathology of adult supratentorial primitive neuroectodermal tumor (SPNET) and to improve the diagnostic level. Methods the clinicopathological and MRI data of 10 cases of adult SPNET proved by surgery and pathology were collected and their imaging features were analyzed retrospectively. The ratio of male to female was 7: 3, and the median age was 45.0 years old. There were 2 cases of headache with syncope and 1 case of numbness of the face and tongue root. All of them were examined by MRI plain enhancement with GE 1.5T MRI scanner. Results all lesions were single, including 5 cases in frontal lobe, 3 cases in temporal lobe, 1 case in parietal lobe and 1 case in corpus callosum knee. No metastases occurred before operation. The lesions were large in size, clear in the boundary, and marked in space occupying effect. There were 5 cases without edema and 2 cases with obvious edema, 2 cases with obvious edema and 2 cases with haemorrhage, and 6 cases with large cystic nodule. Most of the mural nodules were located on the convex surface of the cerebrum, the cystic changes were usually near the midline, and 4 cases were solid, which could be accompanied by focal necrosis with isotropic or low T1WI, high or slightly high T2WI signal intensity. Conclusion the MRI findings of adult SPNET are closely related to histological features and are still confirmed by pathology.
【作者单位】：宁夏医科大学;宁夏医科大学总医院放射科;
【分类号】：R739.4;R445.2

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