超声引导经皮穿刺聚桂醇注射治疗甲状腺囊肿的疗效观察

发布时间：2018-03-31 23:36

本文选题：超声引导　切入点：聚桂醇　出处：《南京医科大学学报(自然科学版)》2015年05期

【摘要】：目的 :探讨超声引导下注射硬化剂聚桂醇治疗甲状腺囊肿的临床疗效及安全性。方法 :采用超声引导经皮穿刺囊腔内注射聚桂醇,治疗甲状腺囊肿共78例。治疗前所有囊肿均接受甲状腺穿刺及细胞病理学检查,以排除恶性病变。治疗时尽量将囊液抽吸净,然后注入约1/3囊腔容积量的聚桂醇进行硬化治疗,每周1次,根据囊肿的缩小情况,共治疗1~4次。结果:178例囊肿共进行166次硬化治疗,3个月后囊肿容积平均缩小71.6%±35.3%,与治疗前相比有显著差异(P0.01);治疗总有效率84.6%(66/78),治愈率52.6%(41/78);2不同容积大小的囊肿治愈率有统计学差异(P0.01),容积5 m L的囊肿治愈率显著高于容积5 m L者(P0.01),但不同容积囊肿的治疗有效率无统计学差异(P0.05);3治疗前后患者甲状腺功能及甲状腺相关抗体滴度无显著变化;4治疗的并发症发生率低,无严重不良反应。结论:超声引导下注射聚桂醇治疗甲状腺囊性病变简单易行、临床效果好,不良反应少,可作为甲状腺囊肿的首选治疗方法之一。
[Abstract]:Objective: to investigate the clinical efficacy and safety of sclerosing agent polycinnamol in the treatment of thyroid cysts. 78 cases of thyroid cysts were treated. Before treatment, all cysts underwent thyroid puncture and cytopathology to exclude malignant lesions. Once a week, depending on how the cyst shrinks, Results the volume of cyst was reduced by 71.6% 卤35.3 months after 3 months, there was significant difference between before and after treatment, the total effective rate was 84.6% 66 / 78, and the cure rate was 52.6% / 782. The cure rate of cyst with different volume was 52.6% / 782. The cure rate of cysts with a volume of 5 mL was significantly higher than that of patients with a volume of 5 mL. However, there was no significant difference in the effective rate of different volume cysts before and after treatment. There was no significant difference in thyroid function and thyroid antibody titer before and after P0.05T3 treatment. The incidence of complications was low in the treatment of DX4. Conclusion: Ultrasound-guided injection of polycinnamol in the treatment of thyroid cystic lesions is simple and easy, with good clinical effect and less adverse reactions. It can be used as one of the first treatment methods for thyroid cysts.
【作者单位】：南京医科大学第一附属医院内分泌科;
【基金】：国家自然科学基金（81102032）
【分类号】：R445.1;R736.1

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