MR灌注加权成像鉴别诊断单发脑转移瘤与高级别胶质瘤

发布时间：2018-04-10 01:35

本文选题：肿瘤转移　切入点：胶质瘤　出处：《中国医学影像技术》2015年02期

【摘要】：目的探讨MR PWI鉴别诊断单发脑转移瘤和高级别胶质瘤的价值。方法回顾性分析脑内单发转移瘤患者18例和高级别胶质瘤患者25例的MR PWI特征。所有患者均接受常规MR平扫、PWI及增强检查。分别测量瘤体、瘤周水肿区(瘤周区)及对侧正常白质区的脑血容量(CBV)值,得出瘤体、瘤周水肿区相对脑血容量(rCBV)值,同时测得时间-信号强度曲线图肿瘤瘤体及瘤周水肿区的相对峰值(rPH)、瘤体的信号强度恢复百分比(PSR),并进行统计学分析。结果高级别胶质瘤和单发脑转移瘤瘤体区的rCBV差异无统计学意义(P0.05);高级别胶质瘤瘤周区rCBV大于单发脑转移瘤(P0.05)。高级别胶质瘤瘤体及瘤周区rPH均高于转移瘤组(P均0.05);高级别胶质瘤瘤体区PSR大于转移瘤(P0.05)。结论 MR PWI可提供瘤体、瘤周区的血流灌注特征以及瘤体血脑屏障破坏情况,有助于鉴别单发脑转移瘤和高级别胶质瘤。
[Abstract]:Objective to evaluate the value of Mr PWI in differentiating single brain metastases from high grade gliomas.Methods Mr PWI features of 18 patients with single brain metastases and 25 patients with high grade gliomas were retrospectively analyzed.All patients received conventional Mr plain scan PWI and enhanced examination.The CBV values of brain blood volume in tumor, peritumoral edema area (peritumoral area) and contralateral normal white matter area were measured, and the relative cerebral blood volume (rCBV) values of tumor, peritumoral edema area were obtained.At the same time, the relative peak value of tumor body and peri-tumor edema area was measured by time-signal intensity curve, and the percentage of signal intensity recovery was analyzed statistically.Results there was no significant difference in rCBV between high grade gliomas and single brain metastases, but the rCBV of high grade gliomas was higher than that of single brain metastases (P 0.05).The rPH of high grade glioma and its surrounding area were higher than those of metastasis group (P < 0. 05), and the PSR of high grade glioma was higher than that of metastasis group (P 0. 05).Conclusion Mr PWI can provide the characteristics of blood flow perfusion and the breakdown of blood-brain barrier in tumor, and can be helpful in differentiating single brain metastases from high grade gliomas.
【作者单位】：福建医科大学附属泉州第一医院影像科;福建医科大学附属第一医院影像科;
【分类号】：R739.41;R445.2

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