乳腺弥散加权成像在乳腺疾病中的作用

发布时间：2018-04-10 07:03

本文选题：弥散加权成像　切入点：动态增强扫描　出处：《中国癌症杂志》2015年08期

【摘要】：背景与目的:乳腺弥散加权成像(diffusion-weighted imaging,DWI)是一种无创伤性的磁共振检查方法,能否替代乳腺磁共振动态增强扫描(dynamic contrast-enhanced,DCE)做为乳腺癌筛查的方法,本研究就此来探讨乳腺弥散加权成像在乳腺良恶性疾病中的作用。方法:74例患者均进行数字乳腺X线、DCE及DWI检查。49例取b值为0、400、600和800 s/mm2。比较DWI和DCE的检出率、灵敏度和特异度;标准化表观弥散系数(apparent diffusion coefficient,ADC)值和ADC绝对值在乳腺癌检出率中的定量分析比较。结果:经手术证实,64/74例病理结果为阳性(38例为恶性病变,26例为良性病变)。经DWI和DCE检查,恶性病变的检出率为100%。b值分别取400、600和800 s/mm2时,DWI在乳腺良恶性病变鉴别中的诊断灵敏度分别为83.33%、90.00%和93.33%,特异度为85.91%、76.19%和72.72%;DCE的灵敏度和特异度分别为86.61%和90.48%;标准化ADC值和ADC绝对值在乳腺癌的检出率中差异无统计学意义(P0.05)。结论:DWI在乳腺疾病的鉴别诊断中,具有一定的优越性,是继常规乳腺磁共振增强检查的重要补充方法。
[Abstract]:Background & objective: diffusion-weighted imaging (DWI) is a non-traumatic magnetic resonance imaging method. Can DWI be used as a screening method for breast cancer, instead of dynamic contrast-enhanced breast imaging (DCE).The purpose of this study was to investigate the role of diffusion-weighted imaging in benign and malignant breast diseases.Methods 74 patients were examined by digital mammography and DWI. The b values were 0400600 s / m ~ (2) and 800 s / m ~ (2) respectively.The detection rate, sensitivity and specificity of DWI and DCE were compared.Results: the pathological results of 74 cases of 64 / 74 cases confirmed by operation were positive and malignant lesions in 38 cases and benign lesions in 26 cases.After DWI and DCE examination,The detection rate of malignant lesions was 400600 and 800 s/mm2, respectively. The sensitivity and specificity of DWI in differential diagnosis of benign and malignant breast lesions were 90.00% and 93.33, respectively. The sensitivity and specificity of DWI were 86.61% and 90.48, respectively. The sensitivity and specificity of DWI were 86.61% and 90.48%, respectively, and the specificity were 85.91% and 72.72%, respectively, and the sensitivity and specificity of DWI in differentiating benign and malignant breast lesions were 86.61% and 93.33%, respectively. The sensitivity and specificity of DWI were 86.61% and 90.48 respectively.There was no significant difference of ADC absolute value in the detection rate of breast cancer (P 0.05).Conclusion in the differential diagnosis of mammary gland diseases, Mr DWI has some advantages and is an important supplementary method to the conventional Mr enhancement examination.
【作者单位】：上海市同仁医院影像科;
【分类号】：R445.2;R655.8

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