磁化传递对比成像和扩散加权成像在中轴型脊柱关节病患者早期骶髂关节炎中的应用

发布时间：2018-04-13 17:31

本文选题：磁共振成像 + 骶髂关节炎　；参考：《放射学实践》2015年06期

【摘要】：目的:研究磁化传递对比成像(MTC)和扩散加权成像(DWI)在中轴型脊柱关节炎患者早期骶髂关节炎中的应用价值。方法:连续搜集炎性腰背痛并疑为中轴型脊柱关节炎患者84例。所有患者均进行MRI检查,通过添加和不添加预饱和脉冲的三维扰相梯度回波序列,两次扫描获得磁化传递对比成像。同时进行平面回波扩散加权成像,b值选取0和600s/mm2。结果:84例患者中16例诊断为不明原因腰背痛患者(对照组)。68例符合国际脊柱关节炎评估协会制定诊断标准为中轴型脊柱关节炎(SpA组)。SpA患者骶髂关节软骨的磁化传递率(MTR)较对照组明显降低(t=4.02,P0.05)。SpA患者的骶骨ADC值较对照组明显升高(P0.05);SpA患者的髂骨ADC值较对照组明显升高(P0.05)。常规磁共振序列检出中轴型脊柱关节炎的敏感度为63.2%,而骶髂关节软骨磁化传递率在检出中轴型脊柱关节炎的敏感度为75%;骶骨和髂骨骨髓ADC值在检出中轴型脊柱关节炎的敏感度为62.3%和72.1%。结论:磁化传递对比成像和DWI成像能够用于检测早期中轴型脊柱关节炎,对比常规MRI成像序列,磁化传递对比成像和扩散加权成像可作为反映早期骶髂关节炎性改变的半定量测量手段。
[Abstract]:Objective: to study the value of magnetization transfer contrast imaging (MTC) and diffusion weighted imaging (DWI) in the early stage of sacroiliac arthritis in patients with central axis spondylitis.Methods: 84 patients with inflammatory low back pain and suspected middle axis spinal arthritis were collected.All patients were examined by MRI and magnetized transfer contrast imaging was obtained by adding and without presaturation pulse of 3D disturbing phase gradient echo sequence.At the same time, the plane echo diffusion-weighted imaging b values were selected 0 and 600 s / m ~ (2).Results among 84 cases, 16 cases were diagnosed as unexplained low back pain (control group, 68 cases were in accordance with the diagnostic criteria established by the International Association for the Assessment of Spinal Arthritis) for magnetization of sacroiliac articular cartilage in spa group of patients with spa.Compared with the control group, the ADC value of sacrum in the patients with P0.05-SpA was significantly higher than that in the control group. The ADC of iliac bone in the patients with P0.05-SpA was significantly higher than that in the control group (P 0.05).The sensitivity of conventional MRI in detecting central axis spondylitis was 63.2, while the magnetic transfer rate of sacroiliac articular cartilage was 75. The ADC value of bone marrow of sacrum and iliac bone was 75.The sensitivity of ganglitis was 62.3% and 72.1%.Conclusion: magnetization transfer contrast imaging and DWI imaging can be used to detect early axial spondylitis and compare with conventional MRI imaging sequence.Magnetic transfer contrast imaging and diffusion-weighted imaging can be used as semi-quantitative measurements to reflect the early sacroiliac arthritis changes.
【作者单位】：华中科技大学同济医学院附属同济医院放射科;
【基金】：国家自然科学基金资助项目(No:81320108013;31170899;81071133)
【分类号】：R445.2;R684.3

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