能谱CT在肌骨肿瘤良恶性鉴别中的价值

发布时间：2018-04-23 17:45

本文选题：体层摄影术 + X线计算机　；参考：《青岛大学》2014年硕士论文

【摘要】：目的：通过对100例病理证实肌骨系统肿瘤所致软组织肿块的能谱CT分析,探讨能谱CT在肌骨系统肿瘤良恶性鉴别中的应用价值。材料与方法：对2011年10月-2013年4月在青岛大学附属医院影像科接受MR扫描并显示有软组织肿块的100例待手术肌骨系统肿瘤病例,应用宝石能谱CT(Discovery CT750, GE Heahhcare, Mliwaukee,美国)进行CT检查。宝石CT扫描模式：CT能谱成像(Gemstone Speelral Imaing GSI)。使用能谱CT的图像后处理技术,选择CNR比选项,测试得最佳单能量值(keV),在单能量图像上选取最佳keV。将感兴趣区置于软组织病变密度均匀的实性区域,避开坏死、囊变、出血及钙化区,由GSI Viewer软件自动生成各ROI40keV-140keV能谱曲线。根据手术病理结果,将100例患者分为良性组(38例)、交界组(10例)、恶性组(49例)和脂肪瘤组(3例)(因脂肪瘤组的曲线呈负值弓背向上形与前三者明显不同,予以单独研究),计算每组平均斜率值：斜率(K40-80keV)=(HU40keV-HU80keV)/80-40。A-C组能谱曲线斜率统计学分析方法采用Kruskal-Wallis秩和检验及Mann-Whitney U方法,以P0.05为差异有统计学意义。结果：恶性组的能谱曲线平均斜率为1.64±1.00,呈速降型,良性组的曲线平均斜率为0.75±0.30,呈缓慢下降型,交界组的斜率介于两者之间为1.34±0.45。良性组斜率小于恶性组斜率(P0.05),良性组斜率小于交界性组斜率(P0.05)。3例脂肪瘤平均斜率为-2.00。结论：CT能谱成像作为一项新的成像模式,在鉴别软组织肿块的良恶性方面有一定价值。负值弓背向上形曲线是含较多脂肪成分肿瘤的特征。
[Abstract]:Objective: to study the value of energy dispersive CT in differentiating benign and malignant tumors of myosseous system from 100 cases of soft tissue masses caused by pathologically proved musculoskeletal system tumors. Materials and methods: from October 2011 to April 2013, 100 cases of myosseous tumors with soft tissue masses were examined by CT(Discovery CT750, GE Heahcaree, Mliwaukee and Mliwaukee (USA) in the Department of Imaging, affiliated Hospital of Qingdao University. Gemstone Speelral Imaing GSI. By using the image post-processing technique of EDS CT and selecting the CNR ratio option, the best single energy value is tested and the best Kev is selected on the single energy image. The region of interest was placed in the solid area with uniform density of soft tissue lesions, avoiding necrosis, cysts, hemorrhage and calcification, and the ROI40keV-140keV energy spectrum curves were generated automatically by GSI Viewer software. According to the results of operation and pathology, 100 patients were divided into benign group (38 cases), borderline group (10 cases), malignant group (49 cases) and lipoma group (3 cases). The average slope value of each group was calculated by using Kruskal-Wallis rank sum test and Mann-Whitney U method. The slope was calculated by Kruskal-Wallis rank sum test and Mann-Whitney U method, and the difference was statistically significant (P 0.05) in HU40keV-HU80keVU / 80keV / / 80-40.A-C group. Results: the mean slope of the energy spectrum curve in malignant group was 1.64 卤1.00, and that in benign group was 0.75 卤0.30. The slope of boundary group was between 1.34 卤0.45 and 0.75 卤0.30, and that of borderline group was 1.34 卤0.45. The mean slope of energy spectrum curve in malignant group was 1.64 卤1.00, and that in benign group was 0.75 卤0.30. The slope of benign group was smaller than that of malignant group (P 0.05), and that of benign group was lower than that of borderline group (P 0.05). The average slope of benign group was -2.00. Conclusion as a new imaging mode, the spectral imaging of CT has a certain value in differentiating benign and malignant soft tissue masses. The upward curve of the back of the negative arch is the characteristic of tumors with more fat components.
【学位授予单位】：青岛大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R730.44;R738.1

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