二维斑点追踪技术评价冠心病患者左室整体收缩功能及其与冠状动脉病变程度的关系

发布时间：2018-04-25 06:55

本文选题：二维超声心动描技术 + 斑点追踪显像　；参考：《安徽医科大学学报》2015年01期

【摘要】：目的应用二维斑点追踪技术(2DSTI)评价冠心病患者左室整体心肌收缩功能,探讨左室整体收缩功能与冠状动脉病变程度的关系。方法收集经冠状动脉造影证实的冠心病患者作为冠心病组(n=51),造影结果阴性者为对照组(n=30),其中冠心病患者根据Gensini积分分为轻度病变组(25分)、中度病变组(25~49分)、重度病变组(≥50分),应用2DSTI技术测量左室整体纵向应变(GLS)、左室整体环向应变(GCS),比较各组间差异,分析其诊断价值,并用各测量值与Gensini积分进行相关性分析。结果与对照组比较,冠心病组GLS、GCS均低于对照组(P0.05),随着冠状动脉病变程度的加重,GLS、GCS进行性减小(P0.05)。受试者工作特征(ROC)曲线显示,GLS、GCS诊断冠心病的敏感性分别为94.1%、66.7%,特异性分别为66.7%、96.7%。相关分析表明冠心病组GLS、GCS与Gensini积分之间呈负相关(r=-0.70,P0.01;r=-0.67,P0.01)。结论冠心病患者心肌收缩功能均有不同程度受损,且随着冠状动脉病变程度的加重而加重,2DSTI可以定量评价左室整体收缩功能,具有临床诊断价值并能反映冠状动脉病变程度。
[Abstract]:Objective to evaluate the global left ventricular systolic function in patients with coronary heart disease (CHD) and to investigate the relationship between the global left ventricular systolic function and the severity of coronary artery disease. Methods the patients with coronary heart disease confirmed by coronary angiography were selected as coronary heart disease group. The patients with negative results were divided into mild lesion group (25 minutes), moderate lesion group (25 ~ 49 minutes) and severe coronary artery disease group (Gensini score). 2DSTI technique was used to measure the global longitudinal strain of left ventricle and the global circumferential strain of left ventricle to compare the difference between the two groups. The diagnostic value was analyzed and the correlation between the measured values and Gensini integral was analyzed. Results compared with the control group, the GCS of the coronary heart disease group was lower than that of the control group (P 0.05). The sensitivity of GCS in the diagnosis of coronary heart disease was 94.1 and 66.7, and the specificity was 66.7, respectively. The correlation analysis showed that there was a negative correlation between GCS and Gensini score in coronary heart disease group. Conclusion the myocardial systolic function in patients with coronary heart disease is impaired to varying degrees, and with the severity of coronary artery disease, 2DSTI can quantitatively evaluate the left ventricular global systolic function, which has clinical diagnostic value and can reflect the degree of coronary artery disease.
【作者单位】：安徽医科大学第一附属医院老年心血管内科;安徽医科大学第一附属医院心血管内科;
【基金】：安徽省科技攻关项目(编号:12010402116)
【分类号】：R445.1;R541.4

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