影响介入性超声治疗卵巢子宫内膜异位囊肿复发率的多因素分析

发布时间：2018-05-04 08:49

本文选题：卵巢子宫内膜异位囊肿 + 介入性超声　；参考：《昆明医科大学学报》2015年07期

【摘要】：目的观察介入性超声治疗卵巢子宫内膜异位囊肿的临床疗效,发现影响手术疗效的相关因素.方法对38例卵巢子宫内膜异位囊肿患者进行介入性超声治疗.术后1月、3月、6月、12月、24月定期随访超声,观察手术疗效.观察患者年龄、囊肿大小、囊肿壁厚度、囊肿分房性、囊肿的侧别、术中无水乙醇留置时间达标与否,术后残留包块与否、术后Gn RH-a使用与否、内异症手术史与否、患者血清CA125阳性与否等十项指标,采用Logistic回归分析这10项指标是否为影响穿刺治疗手术近期、中期复发率的影响因素.结果术后6月Logistic回归分析显示:患者年龄、残余包块与否、囊肿壁厚度OR值大于1,为影响手术疗效的危险因素;术后Gn RH-a的使用,OR值小于1,为影响手术疗效的保护因素.术后24月Logistic回归分析结果显示:年龄、囊肿壁厚度、囊肿侧别OR值大于1,为影响手术中期疗效的危险因素;术后Gn RH-a的使用,OR值小于1,为影响手术中期疗效的保护因素.近期复发率与中期复发率经χ2检验,P0.05,有统计学意义,近期复发率低于中期复发率.结论育龄期子宫内膜异位囊肿患者,年龄较大、囊肿壁厚度较厚、术后有残余包块为影响介入性超声治疗卵巢子宫内膜异位囊肿近期疗效的危险因素,术后药物Gn RH-a的使用为保护性因素.育龄期卵巢子宫内膜异位囊肿者,年龄较大、囊肿壁厚度较厚、双侧囊肿为影响介入性超声治疗卵巢巧克力囊肿中期疗效的危险性因素,药物Gn RH-a的使用为保护性因素.介入性超声治疗卵巢巧克力囊肿近期复发率明显低于中期复发率.
[Abstract]:Objective to observe the clinical effect of interventional ultrasound in the treatment of ovarian endometriosis cysts and to find out the related factors. Methods 38 cases of ovarian endometriosis cysts were treated with interventional ultrasound. One month, three months, six months, twelve months, 24 months after the regular follow-up ultrasound, to observe the results of surgery. Age, size of cyst, thickness of cyst wall, cysts division, side of cyst, time of anhydrous ethanol indwelling, residual mass after operation, use of Gn RH-a after operation, history of endopathy were observed. Ten indexes such as serum CA125 positive or not were analyzed by Logistic regression analysis. Whether these 10 indexes were the influencing factors of the recurrence rate in the near and middle stage of puncture operation. Results six months after operation, Logistic regression analysis showed that age, residual mass or not, or thickness of cyst wall were more than 1, which were the risk factors influencing the outcome of operation, and the use of Gn RH-a was less than 1, which was the protective factor. The results of Logistic regression analysis at 24 months after operation showed that age, thickness of cyst wall, or value of cyst side were more than 1, which were the risk factors influencing the outcome of middle operation, and the use of Gn RH-a was less than 1, which was the protective factor. The recent recurrence rate and the intermediate recurrence rate were significantly lower than those in the middle stage by 蠂 2 test (P 0.05). Conclusion the patients with endometriosis cysts in childbearing age are older and the thickness of the cyst wall is thicker. The residual mass after operation is the risk factor for the short-term curative effect of interventional ultrasound in the treatment of ovarian endometriosis cysts. After operation, the use of Gn RH-a was a protective factor. In the patients with ovarian endometriosis cysts at childbearing age, the thickness of cyst wall was thicker. Bilateral cysts were the risk factors of interventional ultrasound in the treatment of ovarian chocolate cysts, and the use of Gn RH-a was a protective factor. The short-term recurrence rate of interventional ultrasound in the treatment of ovarian chocolate cyst was significantly lower than that in mid-term.
【作者单位】：昆明医科大学第一附属医院妇产科;昆明医科大学第一附属医院心内科;
【基金】：云南省科技厅-昆明医科大学联合专项基金资助项目(2012FB038)
【分类号】：R711.71

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