腰椎间盘突出症患者受压神经根DTI与临床表现的相关性

发布时间：2018-05-04 09:23

本文选题：弥散张量成像 + 神经根　；参考：《中国医学影像技术》2017年12期

【摘要】：目的探讨腰椎间盘突出症患者受压神经根DTI相关参数的变化,及其与基于临床症状的Oswestry功能障碍指数(ODI)、视觉模拟评分(VAS)的相关性。方法 25例经临床和手术证实为单侧神经根受压的腰椎间盘突出症患者纳入本研究,全部患者术前均接受DTI扫描和ODI与VAS评分,ODI、VAS用于评价患者受压神经根对应的特征性下肢疼痛区域。结果腰椎间盘突出症患者患侧与健侧神经根FA值分别为0.26±0.05、0.36±0.05,ADC值分别为(1.69±0.32)×10~(-3)mm~2/s、(1.56±0.21)×10~(-3)mm~2/s;患侧FA值与ODI(r=-0.88,P0.01)及VAS评分(r=-0.66,P0.01)呈负相关,ADC值与ODI(r=0.30,P=0.15)及VAS评分(r=0.36,P=0.08)无相关关系。结论 DTI的FA值可能是量化神经根结构改变的重要参数,腰椎间盘突出症患者神经根结构的损伤可能是产生临床症状的重要原因。
[Abstract]:Objective to investigate the changes of DTI related parameters of compressed nerve roots in patients with lumbar disc herniation and its correlation with Oswestry dysfunction index (Oswestry) and visual analogue score (VAS) based on clinical symptoms. Methods Twenty-five patients with lumbar disc herniation proved to be unilateral nerve root compression were included in this study. All patients underwent DTI scan and ODI and VAS scores before operation to evaluate the characteristic lower limb pain area corresponding to compressed nerve roots. Results in the patients with lumbar disc herniation, the FA values of the affected and healthy nerve roots were 0.26 卤0.05 卤0.36 卤0.05, respectively, and the ADC values were 1.69 卤0.32 脳 10 ~ (-3) mm ~ (-1) and 1.56 卤0.21 脳 10 ~ (-1) 卤0.21) 脳 10 ~ (2) / s, respectively. There was no correlation between the FA value of the affected side and the ODIr-0.88P _ (0.01) and the VAS scores (r = 0.30P ~ (0. 15) and VAS (n = 0.36) P ~ (0.08). Conclusion FA value of DTI may be an important parameter for quantitative changes of nerve root structure, and the injury of nerve root structure in patients with lumbar disc herniation may be an important cause of clinical symptoms.
【作者单位】：中国医科大学附属第一医院放射科;
【分类号】：R445.2;R681.53

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