肾上腺腺瘤宽体探测器CT灌注成像特点

发布时间：2018-05-14 03:00

本文选题：体层摄影术 + X线计算机　；参考：《中国医学影像技术》2017年11期

【摘要】：目的探讨肾上腺皮质腺瘤宽体探测器CT灌注成像特点。方法回顾性分析21例经病理证实的肾上腺皮质腺瘤患者的宽体探测器CT扫描资料。CT灌注(CTP)扫描采用16cm探测器覆盖的轴扫模式,ASiR-V50%,注射对比剂6s后开始行CTP数据采集,共采集26期图像,在第22s、51s及153s获取动脉期、静脉期及延迟期增强图像。测量肾上腺腺瘤(A组)和对侧正常肾上腺结合部(B组)的血流量(BF)、血容量(BV)、平均通过时间(MTT)、达峰时间(TP)及表面通透性(PS)值。比较2组间各参数值的差异,并评价辐射剂量。应用ROC曲线分析CT灌注参数对肾上腺腺瘤的诊断效能。结果 A组的BV、MTT及PS值均低于B组(P均0.05),2组间BF、TP值差异无统计学意义(P均0.05)。以BV、MTT及PS值诊断肾上腺腺瘤的ROC曲线下面积(AUC)分别为0.780、0.762及0.831,以PS值1.37ml/(100g·min)为阈值诊断腺瘤的敏感度为95.2%,特异度为81.0%。平扫、CTP(含增强三期)的有效辐射剂量(ED)分别为(3.20±0.57)、(19.98±1.95)。结论宽体探测器CT灌注成像可为诊断肾上腺皮质腺瘤提供高质量常规三期强化图像,同时提供有效的定量灌注数据。PS值对腺瘤有较高诊断效能。
[Abstract]:Objective to investigate the characteristics of CT perfusion imaging of adrenal cortical adenoma with wide-body detector. Methods the data of 21 cases of adrenal cortical adenoma confirmed by pathology were retrospectively analyzed. Ct perfusion CT scanning was performed with 16cm detector covered by axial scan mode ASiR-V50. The CTP data were collected after 6 seconds of injection of contrast agent. A total of 26 phase images were collected and enhanced images of arterial phase, venous phase and delayed phase were obtained at 22 s, 51 s and 153 s. The mean transit time (MTT), peak time (TPT) and surface permeability (PSV) were measured in adrenal adenoma group A and contralateral normal adrenal junction group B). The difference of parameters between the two groups was compared and the radiation dose was evaluated. The diagnostic efficacy of CT perfusion parameters for adrenal adenoma was analyzed by ROC curve. Results the values of MTT and PS in group A were lower than those in group B (P 0.05). The area under ROC curve was 0.780,0.762 and 0.831, respectively. The sensitivity and specificity of 1.37ml/(100g were 95.2 and 81.0, respectively. The effective radiation dose (EDD) of plain scan CTP (including the third phase of enhancement) was 3.20 卤0.57C (19.98 卤1.95), respectively. Conclusion Wide-body detector CT perfusion imaging can provide high quality conventional three-stage enhanced images for the diagnosis of adrenocortical adenoma, and provide effective quantitative perfusion data .PS value for the diagnosis of adenoma.
【作者单位】：大连医科大学附属第一医院放射科;
【分类号】：R730.44;R736.6

【相似文献】