磁共振双反转恢复序列检测健康人群大脑皮质变异情况的初步研究

发布时间：2018-05-14 03:33

本文选题：双反转恢复序列 + 脑回变异　；参考：《中国医学计算机成像杂志》2017年04期

【摘要】：目的:分析并比较双反转恢复序列(DIR)联合磁共振T1、FLAIR成像对健康人群不同特征大脑皮质变异的检测情况。方法:选择在我院经临床诊断排除中枢神经系统疾病的健康受检者27例,行脑磁共振T1、FLAIR和DIR扫描,统计并比较常规T1、FLAIR成像和联合DIR成像在健康人群中探测到的皮质灰白质交界模糊、脑沟回异常、皮质增厚的变异数,归纳各型皮质变异在大脑中的主要分布特点。结果:在27例健康受检者中,T1、FLAIR共发现皮质变异38处,其中灰白质交界模糊13处,沟回异常21处,皮质增厚4处,人均变异总数为1.407±0.162。T1、FLAIR联合DIR共发现皮质变异69处,其中灰白质交界模糊28处,沟回异常34处,皮质增厚7处,人均变异总数为2.556±0.187。在总皮质变异、灰白质交界模糊数、沟回异常数的检测中,两组比较具统计学显著差异。结论:DIR联合T1、FLAIR可较好显示健康人群的皮质变异。
[Abstract]:Objective: to analyze and compare the detection of cerebral cortical variability in healthy population with dual inversion recovery sequence (DIR) combined with Mr T 1 flair imaging (T1FLAIR). Methods: Twenty-seven healthy subjects who were clinically diagnosed and excluded from central nervous system diseases in our hospital were examined with MRI flair and DIR. The variations of gray and white matter boundary, abnormal sulcus gyrus and thickening of cortex detected by conventional T 1 flair imaging and combined DIR imaging in healthy people were statistically analyzed and compared, and the main distribution characteristics of various cortical variations in the brain were summarized. Results: a total of 38 cortical variations were found in 27 healthy subjects, including 13 blurry junctions of gray and white matter, 21 abnormal sulcus gyrus and 4 thickened cortex. The total number of variations per capita was 1.407 卤0.162. 1 flair combined with DIR found 69 cortical variations. Among them, 28 grey matter junction fuzzy, 34 sulcus gyrus abnormal, 7 cortical thickening, the per capita variation total is 2.556 卤0.187. There were significant differences between the two groups in total cortical variation, gray matter boundary fuzzy number, and abnormal number of sulcus gyrus. ConclusionTwo DIR combined with T 1 flair can better display cortical variation in healthy people.
【作者单位】：复旦大学附属中山医院放射科;复旦大学附属中山医院神经内科;复旦大学附属中山医院体检中心;
【分类号】：R445.2

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