3.0T RESOLVE-DWI与SS-EPI DWI在大鼠颅脑成像中的对比分析

发布时间：2018-05-17 07:27

本文选题：胶质瘤 + 扩散磁共振成像　；参考：《中国医学影像技术》2016年09期

【摘要】：目的探讨高分辨率扩散加权成像(RESOLVE-DWI)在大鼠颅脑胶质瘤成像中的应用价值。方法选取20只Wistar大鼠建立C6胶质瘤模型,并进行常规MRI、单次激发平面回波成像(SS-EPI)DWI及RESOLVE-DWI序列扫描。分别计算SS-EPI DWI和RESOLVE-DWI图像的SNR、CNR及ADC值,评价图像畸变程度,对图像质量进行主观评分,并进行统计学分析。结果 RESOLVE-DWI解剖结构显示规则,颅脑结构轮廓更加接近真实颅脑结构。RESOLVEDWI图像的SNR及CNR均明显高于SS-EPI DWI(P均0.05)。RESLOVE-DWI图像评分高于SS-EPI DWI(P0.05)。RESLOVE-DWI与SS-EPI DWI图像肿瘤中心区和对侧正常脑组织ADC值差异均无统计学意义(P均0.05)。RESLOVE-DWI和SS-EPI DWI图像中肿瘤中心区ADC值均明显高于对侧正常脑组织(P均0.05)。结论RESOLVE-DWI可提供满足临床诊断需求的DWI及ADC图像,较SS-EPI DWI图像质量明显提高。
[Abstract]:Objective to evaluate the value of high resolution diffusion weighted imaging (RESOLVE-DWI) in brain glioma imaging in rats. Methods A C6 glioma model was established in 20 Wistar rats. Routine MRI, single shot planar echo imaging (SS-EPIWI) DWI and RESOLVE-DWI sequence scanning were performed. The SNR and ADC values of SS-EPI DWI and RESOLVE-DWI images were calculated, the degree of image distortion was evaluated, the subjective score of image quality was evaluated, and the statistical analysis was carried out. Results the anatomical structure of RESOLVE-DWI was displayed regularly. The SNR and CNR of craniocerebral structure contours closer to the true brain structure. RESOLVEDWI images were significantly higher than those of SS-EPI DWI(P and 0.05).RESLOVE-DWI image scores higher than those of SS-EPI DWI(P0.05).RESLOVE-DWI and SS-EPI DWI images. There was no significant difference in ADC value between the central area of the tumor and the contralateral normal brain tissue (P In both 0.05).RESLOVE-DWI and SS-EPI DWI images, the value of ADC in the central region of the tumor was significantly higher than that in the contralateral normal brain tissue (P < 0.05). Conclusion RESOLVE-DWI can provide DWI and ADC images which can meet the needs of clinical diagnosis, and the quality of ADC images is better than that of SS-EPI DWI images.
【作者单位】：滨州医学院附属医院影像科;西门子(中国)有限公司磁共振产品事业部;
【基金】：山东省自然科学基金(ZR2011HL038)
【分类号】：R445.2;R739.41

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