Gd-EOB-DTPA肝胆期MRI结合DWI对原发性肝细胞癌的检出价值

发布时间：2018-05-17 07:39

  本文选题：Gd-EOB-DTPA + 扩散加权成像　； 参考：《第三军医大学学报》2015年06期

【摘要】：目的在常规动态对比增强MRI的基础上,探讨Gd-EOB-DTPA增强MR扫描肝胆期结合扩散加权成像序列(DW-MRI)诊断原发性肝细胞癌的价值。方法回顾性分析60例怀疑原发性肝细胞癌(hepatocellular carcinoma,HCC)患者的Gd-EOB-DTPA增强MR扫描动脉期、门脉期、肝胆期及DWI图像资料。分为3组进行阅读和比较,分析影像特征,获得最终影像诊断结果。以手术病理为标准,采用受试者工作特征曲线(ROC)曲线下面积(AUC)分析Gd-EOB-DTPA肝胆期结合DWI序列对HCC的诊断价值。结果 60例患者共发现肝内病灶80个,其中40例患者共诊断56个HCC,其中22个直径≤2 cm。在常规动态对比增强MR扫描基础上,结合Gd-EOB-DTPA肝胆期及DW-MRI不能增加对所有大小的HCC的诊断准确性,但对直径≤2 cm的早期HCC的准确性最高(P=0.024 8),且当仅结合Gd-EOB-DTPA增强MR扫描肝胆期时,其诊断准确性亦高于常规对比动态增强扫描(P=0.043 2),具统计学意义。结论在常规动态对比增强MR基础上,结合Gd-EOB-DTPA增强肝胆期图像和DWI序列有助于诊断直径≤2 cm的早期HCC,可以作为常规MR序列的有效补充。
[Abstract]:Objective to evaluate the diagnostic value of conventional dynamic contrast enhanced MRI (DW-MRI) in the diagnosis of primary hepatocellular carcinoma (HCC) by contrast-enhanced Mr imaging (Mr) combined with diffusion weighted imaging (DW-MRI). Methods the images of arterial phase, portal phase, hepatobiliary phase and DWI in 60 patients with suspected hepatocellular carcinoma (HCC) were analyzed retrospectively. Three groups were divided into three groups to read and compare, analyze the image features, and obtain the final image diagnosis results. The diagnostic value of Gd-EOB-DTPA hepatobiliary phase combined with DWI sequence in HCC was analyzed by using the area under the operating characteristic curve (ROC) curve of the subjects according to the criteria of operation and pathology. Results A total of 80 intrahepatic lesions were found in 60 patients, of which 56 HCC were diagnosed in 40 of them, 22 of which were less than 2 cm in diameter. On the basis of conventional dynamic contrast-enhanced Mr scanning, combining with Gd-EOB-DTPA hepatobiliary phase and DW-MRI could not increase the diagnostic accuracy of HCC of all sizes, but the accuracy was the highest for early HCC with diameter 鈮，

本文编号：1900545