超声引导下粗针穿刺活检在诊断甲状腺结节良恶性方面的应用价值

发布时间：2018-05-20 22:36

本文选题：超声引导 + 甲状腺结节　；参考：《临床耳鼻咽喉头颈外科杂志》2015年20期

【摘要】：目的:评价超声引导下粗针穿刺活检(UG-CNB)在诊断甲状腺结节良恶性方面的应用价值。方法:回顾性分析行UG-CNB的患者224例,其中88例检查后行甲状腺次全切或全切手术,以术后病理结果为金标准,使用统计学方法分析,对比UG-CNB与术后病理结果的一致性。结果:224例甲状腺结节患者共有246个结节进行UG-CNB活检,其中2个结节取样组织过少,UG-CNB未诊断出病理结果。88例手术患者102个结节UG-CNB病理结果阳性76个,其中术后证实恶性72个,良性4个;UG-CNB病理结果阴性26个,术后病理证实恶性4个,良性22个。UG-CNB在甲状腺恶性结节的诊断方面,取材满意率99.19%,敏感度94.74%,特异度84.62%,正确指数79.36%,阳性预测值94.74%,阴性预测值84.62%,假阴性率5.26%,假阳性率15.38%。其诊断有效率与结节大小无关。所有过程并未出现明显并发症。结论:UG-CNB安全有效,导致未出现诊断结果的可能性较小。在诊断甲状腺结节良恶性方面具有较高的应用价值。
[Abstract]:Objective: to evaluate the value of UG-CNB in the diagnosis of benign and malignant thyroid nodules. Methods: two hundred and twenty-four patients with UG-CNB were analyzed retrospectively, 88 of them underwent subtotal thyroidectomy or total thyroidectomy. The results of postoperative pathology were taken as the gold standard. Statistical analysis was used to compare the consistency between UG-CNB and postoperative pathological results. Results A total of 246 UG-CNB biopsies were performed in 224 patients with thyroid nodules, of which 72 were positive for UG-CNB and 72 were confirmed malignant after operation, among which the pathological results were not diagnosed by UG-CNB in 2 out of which, the pathological results were not diagnosed by UG-CNB. The pathological results of benign UG-CNB were negative in 26 cases, malignant in 4 cases confirmed by postoperative pathology, and in the diagnosis of malignant thyroid nodules in 22 cases of benign .UG-CNB. The satisfaction rate was 99.19, sensitivity 94.74, specificity 84.62, correct index 79.36, positive predictive value 94.74, negative predictive value 84.62, false negative 5.26, false positive 15.38. The effective rate of diagnosis was not related to the size of nodules. No significant complications were observed in all procedures. ConclusionTwo-one-UG-CNB is safe and effective, and it is less likely to lead to the absence of diagnostic results. It is valuable in the diagnosis of benign and malignant thyroid nodules.
【作者单位】：哈尔滨医科大学附属肿瘤医院超声科;
【分类号】：R581;R445.1

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