超声射频数据处理技术评价强直性脊柱炎患者颈总动脉内-中膜厚度和血管弹性

发布时间：2018-05-21 05:05

本文选题：超声 + 射频数据处理技术　；参考：《上海医学》2017年08期

【摘要】：目的探讨超声射频数据处理(RF-data)技术评价强直性脊柱炎(AS)患者颈总动脉内-中膜厚度(IMT)和血管弹性的价值,并分析其与临床资料间的相关性。方法选取2015年8月—2016年5月间在上海交通大学附属第六人民医院明确诊断为AS的患者60例,以及同期行体格检查的健康志愿者30名。利用RF-data技术测量所有研究对象的颈总动脉IMT、颈总动脉扩张值(CD)、脉搏波传播速度(PWV)、硬度指数(β)。比较两组间患者的一般资料、颈总动脉IMT、CD、PWV、β值,以年龄、病程、BMI、CRP、红细胞沉降率(ESR)为变量,采用Pearson分析AS患者颈总动脉IMT和PWV与各变量间的相关性。结果 AS组的CRP水平和ESR均显著高于正常对照组(P值均0.01)。AS组左、右侧颈总动脉的IMT、PWV、β值均显著高于正常对照组同侧(P值均0.05),CD显著低于正常对照组同侧(P值均0.05)。AS患者的颈总动脉IMT和PWV与年龄(r=0.386和0.425)、病程(r=0.459和0.528)、ESR(r=0.276和0.316)均呈正相关(P值均0.05),与BMI(r=0.225和0.241)、CRP(r=0.196和0.218)均不相关(P值均0.05)。结论 RF-data技术可自动、准确地检测颈总动脉IMT和血管弹性参数的变化。AS患者颈总动脉IMT、PWV和β值均显著高于正常人,上述参数随着患者的年龄、病程、ESR增加而增加。
[Abstract]:Objective to evaluate the value of radiofrequency data processing (RF-data) in evaluating IMT and vascular elasticity in patients with ankylosing spondylitis (ASA) and to analyze its correlation with clinical data. Methods from August 2015 to May 2016, 60 patients were diagnosed as in the sixth people's Hospital affiliated to Shanghai Jiaotong University, and 30 healthy volunteers underwent physical examination at the same time. The RF-data technique was used to measure the IMTs of the common carotid artery, the dilation value of the common carotid artery, the velocity of pulse wave propagation and the hardness index (尾). The general data of the two groups were compared. The common carotid artery (IMT) CDPWV, 尾 value, age, course of disease and erythrocyte sedimentation rate (ESR) were used as variables to analyze the correlation between IMT and PWV of common carotid artery of as patients by Pearson. Results the levels of CRP and ESR in as group were significantly higher than those in normal control group and 0.01).AS group. In the right common carotid artery, the IMT and PWV of the right common carotid artery were significantly higher than those of the normal control group (P = 0.05C, P = 0.05C, P = 0.386,0.425), and the course of the disease were significantly higher than those of the normal control group (P = 0.366,0.316). There was no correlation between BMI(r=0.225 and BMI(r=0.225, 0.196 and 0.218). Conclusion RF-data technique can automatically and accurately detect the changes of IMT and vascular elastic parameters in common carotid artery. The values of IMT and 尾 of common carotid artery in as patients are significantly higher than those in normal controls. These parameters increase with the age of patients and the course of disease.
【作者单位】：苏州大学附属第一人民医院介入放射科;上海交通大学附属第六人民医院;上海交通大学附属第六人民医院超声医学科上海超声医学研究所;
【基金】：国家自然科学基金(81371574) 上海市人才发展基金(201452) 上海市科学技术委员会动物实验专项基金(15140901400) 上海市交通大学医工交叉面上项目(YG2016MS53)资助
【分类号】：R445.1;R593.23

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