不同b值磁共振弥散加权成像在鉴别前列腺癌和前列腺增生中的价值

发布时间：2018-06-02 09:01

  本文选题：前列腺癌 + 前列腺增生　； 参考：《中国老年学杂志》2017年14期

【摘要】：目的探讨不同b值3.0T磁共振弥散加权成像(DWI)在鉴别前列腺癌(PCa)和前列腺增生(BPH)的价值及合适的b值。方法经穿刺活检或手术病理确诊的PCa患者40例,BPH患者31例,分别接受不同b值DWI扫描获得感兴趣区的表现扩散系数(ADC)值,b值分别为300,800和1 000 s/mm~2,对比分析不同b值条件下PCa与BPH的ADC值差异,并采用受试者工作特征曲线(ROC)确定诊断PCa的灵敏度和特异度。结果不同b值条件下,PCa患者ADC值分别为(1.06±0.06)×10~(-3)mm~2/s,(0.83±0.04)×10~(-3)mm~2/s,(0.73±0.03)×10~(-3)mm~2/s,BPH患者ADC值分别为(1.38±0.06)×10~(-3)mm~2/s,(1.24±0.06)×10~(-3)mm~2/s,(1.18±0.04)×10~(-3)mm~2/s,同一b值条件下,两组结果差异有统计学意义(P0.05)。DWI b 300,DWI b 800,DWI b 1 000诊断PCa的灵敏度和特异度分别为73.8%、76.3%,74.3%、75.0%,88.2%、84.0%。结论 ADC值对鉴别诊断PCa和BPH可提供定性和定量信息,当b=1 000 s/mm~2时,DWI对诊断PCa有较高的灵敏度和特异度。
[Abstract]:Objective to investigate the value and appropriate b value of 3.0T DWI in differentiating prostate cancer (PCA) from benign prostatic hyperplasia (BPH). Methods there were 31 patients with PCa diagnosed by biopsy or operation. The apparent diffusion coefficient (DWI) of the region of interest was 300800 and 1 000 s / m / m ~ (-2), respectively. The difference of ADC value between PCa and BPH was compared and analyzed under different b values. The sensitivity and specificity of diagnosis of PCa were determined by the operating characteristic curve of subjects. 缁撴灉涓嶅悓b鍊兼潯浠朵笅,PCa鎮ｈ，

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