急性损伤所致膝关节软骨下骨髓病变与被覆软骨T2弛豫时间变化的磁共振研究

发布时间：2018-06-05 12:41

本文选题：膝关节 + 软骨　；参考：《中国医学计算机成像杂志》2015年04期

【摘要】：目的:利用T2弛豫时间图(T2 mapping)技术测量膝关节急性损伤后软骨下骨髓病变(subchondral bone marrow lesion,SBML)被覆软骨的T2弛豫时间(T2 relaxation time,T2 RT),并初步探讨膝关节急性损伤后SBML与被覆软骨T2 RT之间的关系及临床意义。方法:收集因急性损伤及临床诊断骨性关节炎(osteoathritis,OA)所致膝关节疼痛前来就诊58例患者,将其分为急性损伤组28例,OA组30例。另外选择20例健康志愿者膝关节作为正常对照组。将膝关节软骨分为三个分区:髌骨软骨、股骨髁软骨及胫骨平台软骨。正常对照组中分别测量三个分区内软骨的平均T2 RT。在急性损伤组和OA组中,测量SBML被覆软骨的T2 RT以及急性损伤组中邻近非SBML区域被覆软骨的T2 RT,并进行比较。测量急性损伤组中SBML的体积,且与其被覆软骨T2 RT进行相关性分析。结果:在正常对照组中,三个膝关节软骨分区内髌骨软骨的T2RT较股骨髁软骨、胫骨平台软骨偏低(P0.05)。急性损伤组SBML被覆软骨的T2 RT较正常对照组膝关节软骨以及急性损伤组中非SBML被覆软骨的T2 RT升高(P0.05),而与OA组SBML被覆软骨之间的T2 RT比较无统计学意义(P0.05);急性损伤组SBML体积与其被覆软骨的T2 RT之间无相关性。结论:利用T2mapping技术测量软骨T2 RT可以发现急性损伤后膝关节SBML被覆软骨在形态变化之前的内部改变;并且提示其可能存在更高发生OA的风险。
[Abstract]:Objective: to measure the T _ 2 relaxation time and T _ 2 relaxation time / T _ 2 RTT of the coated cartilage of subchondral bone marrow lesion after acute knee injury by using T2 relaxation time map and T2 mapping technique, and to explore SBML and coated cartilage T _ 2 after acute knee injury. The relationship between RT and its clinical significance. Methods: 58 patients with knee joint pain caused by acute injury and osteoarthritis OAA were collected and divided into acute injury group (n = 28) and OA group (n = 30). Another 20 healthy volunteers were selected as normal control group. The articular cartilage was divided into three subdivisions: patellar cartilage, femoral condylar cartilage and tibial plateau cartilage. The mean T 2 RTT of cartilage in three subzones was measured in normal control group. The T 2RT of SBML coated cartilage was measured in acute injury group and OA group, and compared with that in acute injury group. The volume of SBML in acute injury group was measured and the correlation with T 2 RT of coated cartilage was analyzed. Results: in the normal control group, the T2RT of patellar cartilage in three subdivision of articular cartilage was lower than that of femoral condylar cartilage, and the tibial plateau cartilage was lower than that of femoral condylar cartilage. The T 2RT of SBML coated cartilage in acute injury group was higher than that in normal control group and non SBML coated cartilage in acute injury group, but there was no significant difference between T2RT and SBML coated cartilage in OA group (P 0.05). There was no correlation between the volume of SBML and T 2 RT of the coated cartilage in the injured group. Conclusion: using T2mapping technique to measure cartilage T 2RT can detect the internal changes of articular SBML coated cartilage before morphologic changes after acute injury, and suggest that there may be a higher risk of OA.
【作者单位】：江苏省徐州市解放军第九七医院影像科;江苏省徐州市徐州医学院附属医院影像科;
【分类号】：R684;R445.2

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