腺样囊性癌的碳离子治疗

发布时间：2018-06-08 00:49

本文选题：腺样囊性癌 + 放射治疗　；参考：《肿瘤防治研究》2017年12期

【摘要】：腺样囊性癌(adenoid cystic carcinoma,ACC)发病率较低,常见于头颈部唾液腺恶性肿瘤中,可手术的患者手术治疗加术后放疗效果尚可,对于无法手术的患者单纯光子线放疗效果不理想。碳离子具有优于常规光子线的放射物理学和生物学特性,有利于对肿瘤的控制和正常组织的保护。目前全世界范围内可以开展碳离子治疗的单位不多,主要集中在德国、日本、美国以及中国上海,治疗的方式主要包括碳离子单独应用治疗ACC、碳离子与调强放射治疗(IMRT)联合治疗ACC、碳离子治疗复发的ACC、碳离子治疗年幼的ACC患者以及正在研究的碳离子放疗与靶向药物及化疗的联合,此类研究可以证实碳离子在临床应用的有效性及安全性。
[Abstract]:The incidence of adenoid cystic carcinoma (ACCs) is relatively low, and it is common in malignant tumors of head and neck. The operative treatment plus postoperative radiotherapy is good, but the effect of simple photon line radiotherapy is not ideal for the patients who can not be operated on. Carbon ions have better radiophysical and biological properties than conventional photon lines, which is beneficial to tumor control and normal tissue protection. At present, there are not many units around the world that can carry out carbon-ion therapy, mainly concentrated in Germany, Japan, the United States and Shanghai, China. The main methods of treatment include the treatment of ACC-alone, the combination of carbon-ion therapy with IMRTACC, the treatment of recurrent ACCs with carbon-ion therapy, the treatment of young patients with carbon-ion therapy, and the study of carbon-ion radiotherapy and targeting. Combination of drugs and chemotherapy, Such studies can confirm the efficacy and safety of carbon ions in clinical applications.
【作者单位】：柳州市中医院肿瘤科;广西医科大学第一附属医院放疗科;
【分类号】：R730.55

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