高场MR扩散加权成像在小细胞肺癌及非小细胞肺癌鉴别诊断中的应用与b值优化

发布时间：2018-06-08 03:28

本文选题：癌 + 非小细胞肺　；参考：《实用医学杂志》2015年06期

【摘要】：目的:探讨扩散加权磁共振成像(diffusion-weighted imaging,DWI)在小细胞肺癌(small cell lung cancer,SCLC)及非小细胞肺癌(non-small cell lung cancer,NSCLC)鉴别诊断中的价值,并优化最佳b值。方法:收集36例经病理证实的肺癌患者,比较不同b值DWI扫描(b=400,600和800 s/mm2)下不同组织学类型NSCLC间表观扩散系数(apparent diffusion coefficient,ADC)的差异。结果:b=600 s/mm2时获得的ADC值的诊断效能ROC曲线下面积(area under curve,AUC)最大(0.892)。结论:b=600 s/mm2时,DWI对SCLC和NSCLC的鉴别诊断有较高的临床应用价值。
[Abstract]:Objective: to investigate the value of diffusion-weighted imaging (DWI) in differential diagnosis of small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), and to optimize the best b value. Methods: a total of 36 patients with pathologically proved lung cancer were collected to compare the difference of apparent diffusion coefficient (ADCC) between different histological types of NSCLC under different b value DWI (400600 and 800s / mm ~ (2). Results the diagnostic efficiency of ADCs obtained at 600 s/mm2 under the ROC curve was the largest (0.892g) under the area under curve. Conclusion the differential diagnosis of SCLC and NSCLC by DWI at 600 s/mm2 is of great clinical value.
【作者单位】：广州医科大学附属肿瘤医院放射科;南方医科大学南方医院影像中心;
【分类号】：R445.2;R734.2

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