甲状腺功能及超声检查在甲状腺良恶性结节老年患者诊断中的临床价值分析

发布时间：2018-06-17 19:26

本文选题：甲状腺功能检查 + 超声检查　；参考：《中国地方病防治杂志》2017年03期

【摘要】：目的探究甲状腺功能检查配合超声检查在鉴别甲状腺良恶性结节老年患者中的应用价值。方法对176例甲状腺结节老年患者的临床病历资料进行回顾性分析,按术后病理学诊断结果将其分为良性组(134例)和恶性组(42例),对其术前甲状腺功能检查结果以及超声检查结果进行对比性分析。结果恶性结节患者的超声影像图像表现为结节边界不清晰、形态不规则、低回声、微钙化,其结节内外血流较为丰富,两组患者在上述超声图像特征上比较存在显著差异(P0.05)。在甲状腺功能指标上,良性组患者的T3、T4、FT3及FT4水平分别为(1.61±0.33)nmol/L、(92.21±13.72)nmol/L、(4.32±0.62)pmol/L、(14.44±3.26)pmol/L,恶性组患者的T3、T4、FT3及FT4水平分别为(4.28±0.59)nmol/L、(14.37±3.19)nmol/L、(1.64±0.34)pmol/L、(95.08±12.89)pmol/L,两组患者比较并未见明显差异(P0.05)。恶性组患者的TSH水平为(2.07±0.63)m IU/L,明显高于良性组(2.44±0.82)m IU/L(P0.05)。随着TSH水平的不断提升,甲状腺恶性结节患者所占的比例也逐渐升高,组间差异有统计学意义(P0.05)。结论对于边界不清晰、形态不规则、结节内低回声、微钙化以及血流较为丰富的甲状腺结节,可初步判定为恶性病变,而TSH水平的异常升高对于甲状腺结节的发生、发展可能有促进作用,可作为甲状腺恶性结节发生的危险因素。
[Abstract]:Objective to explore the value of thyroid function examination combined with ultrasonography in differentiating benign and malignant thyroid nodules in elderly patients. Methods the clinical records of 176 elderly patients with thyroid nodules were retrospectively analyzed. According to postoperative pathological diagnosis, it was divided into benign group (134 cases) and malignant group (42 cases). The results of preoperative thyroid function examination and ultrasound examination were compared. Results the ultrasonic images of malignant nodules showed that the boundary of the nodules was not clear, the shape was irregular, low echo and microcalcification, and the blood flow inside and outside the nodules was abundant. There was a significant difference between the two groups in the characteristics of the above ultrasound images (P 0.05). In terms of thyroid function, the levels of T _ 3T _ 4 FT _ 3 and FT _ 4 in benign group were 1.61 卤0.33 nmol / L, respectively, 92.21 卤13.72 nmol / L, 4.32 卤0.62nmol / L, 14.44 卤3.26 pmol / L, respectively, and the levels of T _ 3T _ 4 / FT _ 3 and FT _ 4 in malignant group were 4.28 卤0.59nmol / L 14.37 卤3.19nmol / L 1.64 卤0.34nmol / L, 95.08 卤12.89pmol / L respectively. There was no significant difference between the two groups. The level of TSH in malignant group was 2.07 卤0.63 m IUP / L, which was significantly higher than that in benign group (2.44 卤0.82mIUP / L). With the increasing of TSH level, the proportion of patients with malignant thyroid nodules increased gradually, and the difference between groups was statistically significant (P 0.05). Conclusion the thyroid nodules with unclear boundary, irregular shape, low echo in the nodules, microcalcification and abundant blood flow can be preliminarily classified as malignant lesions, while the abnormal increase of TSH level is associated with the occurrence of thyroid nodules. Development may play a role as a risk factor for the development of malignant thyroid nodules.
【作者单位】：金华市中心医院超声诊疗科;
【分类号】：R445.1;R581;R736.1

【相似文献】