儿童可逆性胼胝体压部病变综合征临床分析

发布时间：2018-07-10 19:58

本文选题：可逆性胼胝体压部病变综合征 + 磁共振成像　；参考：《临床儿科杂志》2015年11期

【摘要】：目的探讨儿童可逆性胼胝体压部病变综合征(RESLES)的临床及影像学特征。方法回顾性分析2011年12月至2015年5月收治的11例RESLES儿童,对其病因、临床表现、影像学资料、治疗及随访进行总结分析。结果11例患儿中男7例、女4例,年龄(6.24±1.41)岁(8个月~11岁),1型RESLES 8例、2型RESLES 3例。最常见的病因为惊厥发作和感染。除原发病表现,意识障碍是突出的临床表现,其余神经系统表现均轻微或无。8例1型RESLES患儿头颅磁共振(MRI)显示胼胝体压部椭圆形病灶,3例2型RESLES患儿显示整个胼胝体、侧脑室周围及半卵圆中心白质广泛受累,病灶特征为T1WI等或低信号,T2WI、FLAIR像、DWI高信号,ADC低信号。所有患儿复查时(间隔4~30 d)原有病灶均完全消失。随访2个月~3年6个月,头颅MRI均正常。结论儿童RESLES病因复杂,临床表现无特异性,诊断主要依赖头颅MRI,尤其是DWI序列,突出特征为胼胝体压部伴或不伴双侧脑白质的对称性高信号。RESLES预后良好,应避免过度治疗。
[Abstract]:Objective to investigate the clinical and imaging features of reversible corpus callosum syndrome (RESLES) in children. Methods a retrospective analysis of 11 children with RESLES from December 2011 to May 2015 was reviewed. The causes, clinical manifestations, imaging data, treatment and follow-up were analyzed. Results of the 11 children, 7 cases, 4 women, and age (6.24 + 1.41). Age (8 months ~11 years), type 1 RESLES 8, type 2 RESLES 3. The most common disease was convulsive seizures and infection. Except for the original manifestation, the consciousness disorder was a prominent clinical manifestation, the rest of the nervous system showed slight or no.8 cases of RESLES children's head magnetic resonance (MRI) display of the corpus callosum pressure oval focus, 3 cases of 2 type RESLES children showed the whole The corpus callosum, the lateral ventricle and the central white matter in the center of the oval center were widely involved. The lesion was characterized by T1WI or low signal, T2WI, FLAIR image, DWI high signal and ADC low signal. All the children were completely disappeared during the reexamination (interval 4~30 d). The follow-up of 2 months ~3 years and 6 months was normal. Conclusion the etiology of RESLES in children is complex and the clinical manifestations are not specific. The diagnosis mainly depends on the head MRI, especially the DWI sequence, and the prognosis is good for the symmetrical high signal.RESLES characterized by the corpus callosum pressure with or without bilateral white matter, and should avoid overtreatment.
【作者单位】：山东大学附属省立医院小儿神经科;
【分类号】：R741;R445.2

【相似文献】